نتایج جستجو برای: canis lupus lupus

تعداد نتایج: 48725  

Journal: :Arthritis and rheumatism 2012
Travis Hughes Adam Adler Jennifer A Kelly Kenneth M Kaufman Adrienne H Williams Carl D Langefeld Elizabeth E Brown Graciela S Alarcón Robert P Kimberly Jeffrey C Edberg Rosalind Ramsey-Goldman Michelle Petri Susan A Boackle Anne M Stevens John D Reveille Elena Sanchez Javier Martín Timothy B Niewold Luis M Vilá R Hal Scofield Gary S Gilkeson Patrick M Gaffney Lindsey A Criswell Kathy L Moser Joan T Merrill Chaim O Jacob Betty P Tsao Judith A James Timothy J Vyse Marta E Alarcón-Riquelme John B Harley Bruce C Richardson Amr H Sawalha

OBJECTIVE Several confirmed genetic susceptibility loci for lupus have been described. To date, no clear evidence for genetic epistasis in lupus has been established. The aim of this study was to test for gene-gene interactions in a number of known lupus susceptibility loci. METHODS Eighteen single-nucleotide polymorphisms tagging independent and confirmed lupus susceptibility loci were genot...

Journal: :Journal of the American Society of Nephrology : JASN 2015
Tamara K Nowling Andrew R Mather Thirumagal Thiyagarajan María José Hernández-Corbacho Thomas W Powers E Ellen Jones Ashley J Snider Jim C Oates Richard R Drake Leah J Siskind

Nearly one half of patients with lupus develop glomerulonephritis (GN), which often leads to renal failure. Although nephritis is diagnosed by the presence of proteinuria, the pathology of nephritis can fall into one of five classes defined by different forms of tissue injury, and the mechanisms involved in pathogenesis are not completely understood. Glycosphingolipids are abundant in the kidne...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2016
Daniel J Birmingham Joshua E Bitter Ezinne G Ndukwe Sarah Dials Terese R Gullo Sara Conroy Haikady N Nagaraja Brad H Rovin Lee A Hebert

BACKGROUND AND OBJECTIVES Autoantibodies to complement C1q (anti-C1q) are associated with the diagnosis of lupus nephritis. In this study, we compare anti-C1q IgG with another complement autoantibody, anti-C3b IgG, as a biomarker of lupus nephritis and lupus nephritis flare. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Our investigation involved the Ohio SLE Study, a prospective observationa...

2011
Friederike Range Zsófia Virányi

The ability to coordinate with others' head and eye orientation to look in the same direction is considered a key step towards an understanding of others mental states like attention and intention. Here, we investigated the ontogeny and habituation patterns of gaze following into distant space and behind barriers in nine hand-raised wolves. We found that these wolves could use conspecific as we...

2001
Chris T. Darimont Paul C. Paquet Chris Darimont

A professional biologist, he has studied other elusive wildlife species including Marbled Murrelets, Canada Lynx, and Northern Goshawks. Paul first introduced Chris to wolf research in 1998 when Chris worked for the Central Rockies Wolf Project. Chris plans to continue coastal wolf research as a graduate student. He operates Darimont Environmental. in the School of Forestry. He is a member of s...

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