A 68 year old woman with sporadic Creutzfeldt-Jakob disease is described, who neither showed characteristic EEG abnormalities nor a positive test of the neuronal protein 14-3-3 or neuron specific enolase (NSE) in CSF, despite a clinical presentation with ataxia of cerebellar type, rapidly progressive dementia, myoclonus, and marked hyperintense signal abnormalities in the deep cortical layers a...

work document excellent outcomes for all physicians, including anesthesiologists, treated and monitored by PHPs. To summarize each, Pelton and Ikeda reported a 10-yr follow-up of 255 physicians (including 35 anesthesiologists) successfully completing the California Diversion Program with excellent outcomes. They concluded that anesthesiologists had “equal chance of recovery and contradicts the ...

To the Editor: During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. Initial testing of the virus found it susceptible to neuraminidase inhibitors and resistant to adamantanes (1,2). As of March 5, 2010, only 264 cases of oseltamivir-resistant pandemic (H1N1) 2009 infection had been reported to the World Health Organization, but the number of cases has been...

model of accelerated aging symptoms established by Takeda et al. SAM is composed of eight aging-prone (SAMP) lines and three resistant (SAMR) lines. SAMP8 shows marked impairment of learning and memory. We previously reported several neurochemical alterations in the hippocampus of aged SAMP8 such as i) the elevated amounts of glutamate and glutamine in the hippocampus, ii) the decreased release...

Inverse optimization of parameters offers an economical means to infer soil hydraulic properties from in situ measurements of infiltration. We evaluated optimization strategies to inversely estimate soil hydraulic parameters using field measured tension disc infiltrometer data. We estimated the parameters n, , and Ks of the van Genuchten-Mualem (VGM) model, and a piecewise representation of con...

how to cite this article: karimzadeh p, jafari n, nejad biglari h, jabbehdari j, khayat zadeh s, ahmad abadi f, lotfi a. neurometabolic diagnosis in children who referred as neurodevelopmental delay (a practical criteria, in iranian pediatric patients). iran j child neurol. summer 2016; 10(3):73-81.   objective we aimed to investigate the clinical and para clinical manifestations of neuro metab...

171 In vitro, brain-derived endothelium loses several blood-brain barrier (BBB) characteristics such as-glutamyl transpeptidase, tight junctions and the polarized transport of amino acids. However, these features are regained during co-culture with astroglial cells or their conditioned medium. To determine if similar BBB deficits would occur in situ when micro-vessels were denuded of their astr...

Introduction NAA (N-acetyl-aspartate) is the second most abundant molecule in the CNS (after glutamate), its MRS signal is commonly used as a putative marker of viable neurones, and yet little is known about its function. Furthermore, recent data from cell culture has raised the possibility of an additional cellular contribution of NAA from nonneuronal origins, principally in isolated mature ol...

The reaction is studied with the H1 detector at HERA. The data cover momentum transfers between and and correspond to an integrated luminosity of "!$# %'&)(+* . The differential cross section ,'-/.0,1 is compared to the Standard Model expectation for neutral current scattering and analysed to search for 2 3 452 3 6 6 4 contact interactions. No evidence for new phenomena is observed. The results...

3 Tappin DM, King C, Paton JY. Lower oesophageal pH monitoring-a useful clinical tool. Arch Dis Child 1992;67:146-8. 4 Evans DF, Robertson CS, Ledingham SJ, Kapila L. Oesophageal pH monitoring for gastrooesophageal reflux: a United Kingdom study. J Pediatr Surg 1991;26:682-5. 5 Cucchiara S, Staiano A, Boccieri A, et al. Effects of cisapride on parameters of oesophageal motility and on prolonged...