Background and objectives: Cancer is a public health problem all over the world. Herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity. Methods: Twenty seven medicinal plants from southern Iran provinces have been extracted with methanol and screened for their cytotoxic ac...

Calotropis gigantea (L.) R.Br. (Asclepiadaceae) is a perennial herb used as traditional medicine. This an important plant however, presently under the threat of extinction. While entire for skin diseases, powdered root bark able to cure elephantiasis, dysentery and leprosy. The stem gastrointestinal respiratory track diseases including dysentery, spleen complaints, ringworm pneumonia. toothache...

Calotropin isolated and characterized from the roots of Calotropis procera when administered to gerbils (25mg/kg b.wt) and rabbits (25mg; kg b.wt) each day for a period of 30 days inhibited the process of spermatogenesis. The population of spermatids was depleted by 65% and 94% in gerbils and rabbits. The seminiferous tubules and the Leydig cell nuclei diameters were reduced in both the species...