A novel photoinduced electron transfer (PET) based substituted calix[4]arene fluoroionophore has been used for the selective recognition of tryptophan (L-Trp) and histidine (L-His) by emission spectroscopy. The detection limit of the synthesized receptor was found to be 0.00826 nM for L-Trp and 0.00158 nM for L-His. Moreover, this probe has been applied for the recognition of L-Trp and L-His fr...

Abstract Self‐folding cavitands represent the quintessential form of bioinspired synthetic receptors, featuring deep hydrophobic cavities that engage in host‐guest chemistry reminiscent operating biomolecules. Although remarkable proof‐of‐concept applications have been reported, narrow and rigid spaces legacy resorcin[4]arene derived hosts constitute a liability towards development specific cat...

Since melanocytes are the origin of melanoma and some skin disorders such as melasma, they are important cells from the perspective of medicinal chemistry. Therefore, a medication that can simultaneously overcome these diseases will be a successful potential therapeutic agent. Arbutin with phenolic structure is a powerful natural anti-tyrosinase agent. Hence, the phenolic structure of this drug...

synthesis and cation selectivity of 25, 27, dipropoxy-26, 28, di-propoxy 5, 11, 17, 23, ptert-butyl calix[4]arene are studied in acetonitrile solution. the stability constants of differentcomplexes of calixarene (as a ligand) with alkali metal cations are determined at 25 °c by usingspectrophotometric technique.on the basis of calculations, complexation of calixarene with cs+and li+ are more fa...

A new calix[6]azacryptand ligand has been prepared in six steps starting from 1,3,5-trismethoxycalix[6]arene. An X-ray study shows that this ligand has a sterically protected tren-based binding site at the bottom of a polyaromatic bowl and ether sites around its rim. It binds Zn(2+) to give a complex in which zinc is in a trigonal bipyramidal geometry with a water bound in one apical position a...

An amphiphilic calix[4]arene with sulfonate groups on the lower rim has been investigated as a buffer additive for separation of positional isomers by capillary electrophoresis. Addition of the compound to the running buffer led to successful separation of positional isomers of nitrophenols, dinitrobenzenes, and benzenediols. Association constants between the calixarene and the analytes indicat...

Recent advances in the area of recognition and sensing have shown that artificial receptors derived from extended calix[4]arenes bearing multiple π-conjugated fluorophoric or chromophoric systems have found useful to enhance binding affinity, selectivity and sensitivity for recognition and sensing of a targeted ion or molecule. A comprehensive review of various π-conjugation-extended calyx[4]ar...

A calix[4]arene acetylene (C4AE)-modified gold surface is successfully constructed in situ via click chemistry. The functionalized surface is used for selective recognition of paraquat by a wettability switch. Impedance measurements showed that the surface also expresses recognition for paraquat with a high sensitivity of 10 pM. The recognition mode, based on host-guest inclusion, is studied by...