P63 may have a role in tumorigenesis and cytodifferentiation of odontogenic lesions. We investigated the immunohistochemical expression of P63 in a total of 30 cases of odontogenic cysts and tumors. The percentage of positive cells was calculated in the lining of odontogenic cysts and islands of ameloblastoma. P63 expression was evident in all types of odontogenic lesions. P63 was expressed thr...

BACKGROUND AND OBJECTIVE: Calcifying odontogenic cyst is an uncommon developmental cyst. It accounts for only 1% of jaw cysts and uncommonly occurs with odontoma. Herein, we report a case of calcifying odontogenic cyst, associated with complex odontoma. CASE REPORT: The patient was a 12-year-old girl with complaints of painless swelling in the mandibular first premolar. In radiographic examinat...

A 14-year-old Black female was referred for management of an asymptomatic swelling in her right maxilla. The lesion measured 3cm across, was localised lateral to the right ala of the nose, felt bony hard in some areas and soft in others, and was continuous with the maxillary buccal plate. It occupied the right anterior vestibule but there was no palatal expansion. A panoramic radiograph showed ...

Odontogenic tumors and cysts, arising in the jawbones, grow by resorption and destruction of the jawbones. However, mechanisms underlying bone resorption by odontogenic tumors/cysts remain unclear. Odontogenic tumors/cysts comprise odontogenic epithelial cells and stromal fibroblasts, which originate from the developing tooth germ. It has been demonstrated that odontogenic epithelial cells of t...

A calcifying odontogenic cyst may be associated with tumors, particularly odontomas. However, the association between cysts and is rare. This study aims to report first case of a an antral pseudocyst. male patient presented tumor lesion in his right maxillary alveolar ridge 6 months evolution painful symptoms . An excisional biopsy was performed, histopathological diagnosis pseudocyst issued. T...

background: vascular endothelial growth factor (vegf) is capable of initiating angiogenesis in blood vessels and may act as mitogenic agent for epithelium of odontogenic cysts and tumors. this study was conducted to evaluate the role of epithelial vegf expression in odontogenic cysts and ameloblastoma and its correlation with argyrophilic nucleolar organizer region counts to assess its role in ...

There are few studies on bucco-maxillary lesions in children and adolescents, and reports on odontogenic tumors (OT) are scanty. Comparison among the available data is difficult due to differences in the criteria used in each study. The aim of the present work was to perform a retrospective study of OT in patients aged up to 20 years diagnosed at a center specialized in histopathologic diagnosi...

Odontogenic fibroma (OF) is considered an unusual, benign mesenchymal neoplasm and one of the most little-understood lesions amongst all odontogenic neoplasms. The incidence rate of the tumor is from 0% to 5.5%. WHO classified them into intraosseous or central and extraosseous or peripheral variants. It chiefly consists of fibroblastic tissue with an inconsistent amount of inactive appearing od...

controversies existed regarding the relationship between non-neoplastic cystic lesions and solid tumor masses. The so-called COC shows great diversity in the spectrum of clinical behavior and histopathological features, including cystic, solid (neoplastic), and aggressive (malignant) variants, because of which different categorization and nomenclature for the lesion have been proposed. In the 2...