OBJECTIVE People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS The Archimedes model was used to estimate the proportion of myocardial infarctions that would be prevented by maintaining insulin...

BACKGROUND Conventional coronary artery disease (CAD) risk factors fail to explain nearly 50% of CAD events. This study examines the association between electron-beam tomography (EBT) coronary artery calcium (CAC) and cardiac events in initially asymptomatic low- to intermediate-risk individuals, with adjustment for the presence of hypercholesterolemia, hypertension, diabetes, and a history of ...

coronary artery disease (cad) including myocardial infarction (mi) as its complication, is one of the most common heart diseases worldwide and also in iran, with extremely elevated mortality. cad is a multifactorial disorder. twin and family studies at different loci have demonstrated that genetic factors have an important role in the progression of cad. many studies have reported a significant...

OBJECTIVES The aim of this study was to evaluate the relationship between pulse wave velocity and carotid intima-media thickness (IMT) in patients with different cardiovascular risk factors. MATERIAL AND METHODS This prospective study included 223 patients with at least 2 risk factors for atherosclerosis, divided based on the presence of coronary artery disease (CAD): 140 patients with angiog...

OBJECTIVES This study prospectively examined whether the levels of high remnant-like lipoprotein particles (RLP) cholesterol have a significant risk and influence prognosis in patients with coronary artery disease (CAD) and type II diabetes mellitus (DM). BACKGROUND Several studies have shown that triglyceride-rich lipoproteins contribute to atherosclerotic complications in type II DM. Howeve...

INTRODUCTION South Asian immigrants (SAIs) in the US exhibit higher prevalence of coronary artery disease (CAD) and its risk factors compared with other ethnic populations. Conventional CAD risk factors do not explain the excess CAD risk; therefore there is a need to identify other markers that can predict future risk of CAD in high-risk SAIs. The objective of the current study is to assess the...

OBJECTIVE Type 1 diabetes increases the risk for coronary artery disease (CAD), but limited information is available regarding the early natural history of this process. Electron beam tomography (EBT) can measure coronary artery calcification (CAC), an early marker for CAD. This study was designed to assess the prevalence and risk factors for CAC in young adults with established type 1 diabetes...

over a period of four years, we followed 200 male cases (female patients were excluded from this study because from early childhood, the majority of iranian girls have their ears pierced which tends to distort the ear lobe and renders the diagnosis of the crease difficult) of proved coronary artery disease (angina pectoris, coronary insufficiency, and myocardial infarction) in a private clinic ...

Carotid disease is a common finding in patients with coronary artery disease (CAD) and its presence is associated with worse clinical outcomes. Intima-media thickness provides incremental value over traditional risk factors in predicting cardiovascular events; however, it does not predict the absence of CAD or its extent and severity. The presence of carotid plaques is associated with an increa...