‘What is the best choice of first-line treatment in men with poor prognosis metastatic castration-resistant prostate cancer (mCRPC)?’ Up until today, this important topic under debate daily practice. Although guidelines advocate use taxanes as first CRPC1Gillessen S. Attard G. Beer T.M. et al.Management patients advanced cancer: report consensus conference 2019.Eur Urol. 2020; 77: 508-547Abstra...