two bonding models i.e cumullenic and acetylenic models have been proposed to account for thebonding patterns in linear carbon clusters while the bonding patterns in cyclic and 3d geometries of theseclusters have remained ambiguous.this work presents the bonding patterns in various c4 and c5 pure clusters at mp2/aug-cc-pvtz level oftheory. this subject is studied in the light of modern bonding ...

Abstract Background Humanized anti-C5 monoclonal antibody therapeutics has been heralded as a breakthrough treatment for Paroxysmal Nocturnal Hemoglobinuria and atypical Hemolytic Uremic Syndrome. Therapeutic drug monitoring is currently not widely available but assessing complement blockage maybe useful to monitor optimize Eculizumab or Ravlizumab efficacy. Recent studies have suggested using ...

The first known human kindred with hereditary deficiency of the fifth component of complement (C5) was documented in the accompanying report. This study examines several biological properties of C5-deficient (C5D) human serum, particularly sera obtained from two C5D homozygotes. The proband, who has inactive systemic lupus erythematosus is completely lacking C5, while her healthy half-sister ha...

1. Abe M. Complement activation and inflammation. Rinsho Byori 2006;54:744–56. 2. Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, et al. TRAF1-C5 as a risk locus for rheumatoid arthritis – a genomewide Study. N Engl J Med 2007;357:1199–209. 3. Kurreeman FA, Padyukov L, Marques RB, Schordi SJ, Seddighzadeh M, StoekenRijsbergen G, et al. A candidate gene approach identifies the TR...

The 14-channel Ames Airborne Tracking Sunphotometer (AATS) was operated on a Jetstream 31 (J31) aircraft in March 2006 during MILAGRO/INTEX-B (Megacity Initiative-Local And Global Research Observations/Phase B of the Intercontinental Chemical Transport Experiment). We compare AATS retrievals of spectral aerosol optical depth (AOD) and related aerosol properties with corresponding spatially coin...

Replication incompetent human adenovirus serotype 5 (HAdV-C5) has been extensively used as a delivery vehicle for gene therapy proteins and infectious disease antigens. These vectors infect replicating and nonreplicating cells, have a broad tissue tropism, elicit high immune responses and are easily purified to high titers. However, the utility of HAdV-C5 vectors as potential vaccines is limite...

A series of anthraquinone-imide-based dimers, C5 -AQI-Si2, C5 -AQI-Si3, C5 -AQI-Si4, and C5 AQI-Si8, have been prepared by the hydrosilylation of N-(hex-5-enyl)-6-(40-((S)-2-methylbutoxy)phenyl)anthraquinone-2,3-dicarboxylic imide and hydride-terminated siloxanes with different lengths. Their liquid crystalline behaviors, and piezochromic and near-infrared electrochromic properties have been ch...

Lesions of the nerve produce weakness of flexion at the elbow and weakness of supination. The biceps is an important supinator. There is sensory loss on the lateral side of the forearm. The brachialis muscle receives innervation from both the musculocutaneous nerve and the radial nerve. [7, 8] One study found that the musculocutaneous nerve contributes to 42% of the muscle power that flexes the...