BACKGROUND The objective of this study was to determine the prevalence of Chlamydia trachomatis among both men and women seeking help at an infertility clinic, and to prospectively follow the effect of previous infection on pregnancy rates and pregnancy outcome after a long follow-up period (mean 37 months). METHODS A total of 244 infertile couples was tested for C. trachomatis IgG antibodies...

As reliable data on Chlamydia trachomatis infection in Italy are lacking and as there is no Italian screening policy, epidemiological analyses are needed to optimise effective strategies for surveillance of the infection in the country. We collected data from 6,969 sexually active women aged 15 to 55 years who underwent testing for endocervical C. trachomatis infection at the Cervico-Vaginal Pa...

The in vitro activities of nemonoxacin, levofloxacin, azithromycin, and doxycycline were tested against 10 isolates each of Chlamydia trachomatis and Chlamydia pneumoniae. The MICs at which 90% of the isolates of both C. trachomatis and C. pneumoniae were inhibited (MIC90s) were 0.06 μg/ml (range, 0.03 to 0.13 μg/ml). The minimal bactericidal concentrations at which 90% of the isolates were kil...

Background: Chlamydia trachomatis (C. trachomatis) is the most common bacterial sexually transmitted infection (STI). C. trachomatis has a high rate of asymptomatic infection approximately 80% of cases in females, and 45% in males, are estimated to be asymptomatic. Objective: The aim of this study was to to detect the prevalence of C. trachomatis among women with chronic cervicitis, abortion, f...

OBJECTIVES To compare endourethral swabs and urine as diagnostic specimens for the detection of genital Chlamydia trachomatis infection using the polymerase chain reaction (PCR), in male patients attending a genitourinary clinic and to assess whether the first endourethral swab used solely for diagnosing gonococcal infection could be used for C trachomatis detection as well. METHODS Two endou...

PURPOSE Chlamydia trachomatis is the leading infectious cause of blindness. The goal of the current study was to search for biomarkers associated with C. trachomatis-induced ocular pathologies. METHODS We used a whole genome scale proteome array to systematically profile antigen specificities of antibody responses to C. trachomatis infection in individuals from trachoma-endemic communities wi...

We genotyped Chlamydia trachomatis strains from 45 women or men living in either a rural indigenous community or in urban heterosexual communities. We found six different C. trachomatis serovars: E (n = 22; 48.9%), F (n = 10; 22.2%), J/Ja (n = 5; 11.1%), D/Da (n = 4; 8.9%), G (n = 3; 6.7%), and K (n = 1; 2.2%). The distribution of C. trachomatis serovars among members of the indigenous rural an...

Received: 25/Nov/2007, Accepted: 6/Feb/2008 Objective: The objective of this research was to determine the prevalence of genital C. trachomatis infection in asymptomatic women by using highly sensitive nested-polymerase chain reaction (PCR) in urine sample. Materials and Methods: One hundred-forty asymptomatic women were randomly selected from those who attended gynecology out patient departmen...

A total of 707 cultures for Chlamydia trachomatis were obtained from healthy teenage girls attending an adolescence clinic for family planning. Apart from sampling from the endocervix, specimens were also obtained from outside the squamocolumnar junction and from the posterior fornix and cultured separately in order to study whether it was possible to improve the detection rate of C trachomatis...

BACKGROUND/OBJECTIVES Few studies of Chlamydia trachomatis incidence, especially among men, and most studies of C. trachomatis in US military populations are cross sectional prevalence surveys. A population based retrospective cohort was used to determine risk factors for repeat diagnoses of genital C. trachomatis infections among male and female soldiers with previous C. trachomatis infections...