Refractories, materials that can withstand high temperatures, play an important role in the iron and steel sector which alone accounts for ~70% of total refractories pro‐ duced. In this chapter, detailed wettability and interfacial phenomena investiga‐ tions on alumina-carbon and zirconia-carbon refractories at steelmaking temperatures. The wettability between refractory substrates and molten i...

Pomalidomide and low-dose dexamethasone (PomDex) is standard treatment of lenalidomide refractory myeloma patients who have received >2 prior therapies. We aimed to assess the safety and efficacy of the addition of oral weekly cyclophosphamide to standard PomDex. We first performed a dose escalation phase 1 study to determine the recommended phase 2 dose of cyclophosphamide in combination with ...

Herein, a novel refractory Nb30Mo30Ti20Co20 (at. %) high-entropy superalloy (RHESA) is introduced. Annealing at 1200 °C led to the precipitation of semi-coherent individual (Co, Ti)-rich B2, (Ti, O)-rich fcc (Ti-rich oxides), and hierarchical B2 + nanoparticles in (Nb, Mo)-rich RHESA bcc phase. dispersoids were dominant, they nucleated heterogeneously because coherency ensured by Baker–Nutting ...

A change in subtask order in the psychological refractory period (PRP) paradigm increases the effect of stimulus onset asynchrony (SOA) on the second response. We used a paradigm with cued, randomly determined subtask order to test the hypothesis that this SOA by order switch overadditivity reflects order control, via "copying" stimulus order. In Experiments 1a and 1b, overadditivity was eviden...

introduction biotinidase deficiency is a life threatening inborn error of metabolism specially when delayed in diagnosis. we report a 2-month-old male infant that presented with refractory infantile spasm, alopecia and seborrheic dermatitis. with a high suspicion of the biotinidase deficiency we started biotin 10 mg daily orally before definite diagnosis was made. rapid treatment was life-savin...

introduction: management of early relapsed or refractory lymphoma [hodgkin & non- hodgkin lymphoma (hl & nhl)] is a matter of problem, especially when hematopietic stem cell support is not available. the aim of this study was to evaluate effectiveness of iev regimen ( ifosfamide, epirubicin, vp16), in lymphoma patients who are not candidate for stem cell transplantation. because the majority of...

introduction: prostate cancer is one of the most common cancers among males and the second factor resulting to death due to cancer among them.(1) the median age of its diagnosis is 65 years. the initial treatment includes androgen ablation or orchiectomy.(2, 3) in case of patient’s hormone refractory, chemotherapy would be substituted. the objective of this study is the consideration of intermi...

Introduction Biotinidase deficiency is a life threatening inborn error of metabolism specially when delayed in diagnosis. We report a 2-month-old male infant that presented with refractory infantile spasm, alopecia and seborrheic dermatitis. With a high suspicion of the biotinidase deficiency we started biotin 10 mg daily orally before definite diagnosis was made. Rapid treatment was life-savin...

aluminium phosphide (alp) is used to kill rodents in grain storage. it produces phosphine gas which is toxic for mitochondria. the exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. this poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...

We used INAA to determine the bulk compositions of 10 carbonaceous chondrites of uncertain classification. Most samples were analyzed in duplicates and the averaged results are given in Table 1 and shown in Figs. 1 and 2. Thin sections were examined microscopically. Mgand Cr-normalized abundance patterns show clear identifications for four specimens (Fig. 1. The others have nonindicative elemen...