The pre-Botzinger complex (pBC) is a vital subcircuit of the respiratory central pattern generator. Although the existence of neurons with pacemaker-like bursting properties in this network is not questioned, their role in network rhythmogenesis is unresolved. Modeling is ideally suited to address this debate because of the ease with which biophysical parameters of individual cells and network ...

Eukaryotic transcription occurs in bursts that vary in size and frequency, but the contribution of individual core promoter elements to transcriptional bursting is not known. Here we analyze the relative contributions to bursting of the individual core promoter elements-CCAAT, TATAA-like, Sp1BS, and Inr-of an MHC class I gene in primary B-cells during both basal and activated transcription. The...

The principal objectives of this present work were to develop novel coated fabrics in olive green (OG) colour serve as canopy for inflatable military tent (IMT) forest area. Two varieties developed by coating specific grade aliphatic thermoplastic polyurethane (TPU) on Nylon and one more with plasticized polyvinyl chloride (PVC) Polyester fabric. construction parameters properties the substrate...

Glucose triggers bursting activity in pancreatic islets, which mediates the Ca2+ uptake that triggers insulin secretion. Aside from the channel mechanism responsible for bursting, which remains unsettled, it is not clear whether bursting is an endogenous property of individual beta-cells or requires an electrically coupled islet. While many workers report stochastic firing or quasibursting in s...

We report on the discovery of a novel class of bursting rhythms, called amplitude-modulated bursting (AMB), in a model for intracellular calcium dynamics. We find that these rhythms are robust and exist on open parameter sets. We develop a new mathematical framework with broad applicability to detect, classify, and rigorously analyze AMB. Here we illustrate this framework in the context of AMB ...

A svéd Totalförsvarets Forskningsinstitut védelmi kutatóintézet 2019-ben és 2020-ban kiadott tanulmány kötetei (Bursting the Bubble – Understanding Full - Spectrum of Russian A2AD Threat and Identifying Strategies for Counteraction, valamint a Beyond Bursting in Baltic Sea Region: Capabilities, Countermeasures, Implications1) azt vizsgálta, hogy kalinyingrádi orosz exklávéba telepített A2/AD ké...