BACKGROUND The local treatment of burn wounds has long been a subject of debate. The objective of this study was to compare the cost and the effectiveness of Moist Exposed Burn Ointment -MEBO versus a combination of povidone iodine plus bepanthenol cream for partial thickness burns. METHODS The study was carried out in the Burn Center of a state hospital in Athens, Greece. 211 patients needin...

Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of...

Lucilia sericata maggots have beneficial properties; however, their protective effects on burn wounds have yet to be fully elucidated. In the present study, a deep second‑degree burn rat model was used to investigate the burn wound healing properties of aqueous extract of maggots (MAE). The anti‑inflammatory, antioxidative and antibacterial activities were examined. In addition, the protein exp...

Objective-  To evaluate the role of autogenous bone marrow (BM), in the healing of experimentally induced burn wound in rats. Design- Experimental in-vivo study.   Animals- 20 adult male white New Zealand rabbits.   Procedures- Two burn wounds were created under general anesthesia using a 100 W electric soldering iron, heated to the point of redness (about 800° C) on each side of the back, 4...

BACKGROUND The present study was designed to evaluate the potential of isoquercetin-based cream formulation on scald burn wound injury in rats. METHODS Four isoquercetin-based cream formulations viz. 0.01, 0.02, 0.04, and 0.06 % w/w were prepared. Cream base and standard anti-burn cream containing silver sulfadiazine were also used for comparison. Scald burn was given to rats by pouring water...

background and objectives: infection is the most common problem following burn injury. selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including pseudomonas aeruginosa. multi-drug resistant pseudomonas aeruginosa has frequently been reported as the cause of nosocomial outbreaks of infection in b...

Antimicrobial therapy remains to be the most important method of wound infection treatment. Systemically administered antimicrobials may not achieve therapeutic level in wound. On the other hand, in the absence of surgical debridement (due to any reason), most topically applied antimicrobials cannot penetrate the wound in therapeutic amount due to the presence of eschar. Burn eschar is a protei...

Accurate and timely assessment of burn wound severity is a critical component of wound management and has implications related to course of treatment. While most superficial burns and full thickness burns are easily diagnosed through visual inspection, burns that fall between these extremes are challenging to classify based on clinical appearance. Because of this, appropriate burn management ma...

The effects of Aloe vera on microcirculation and levels of TNF-α and IL-6 were investigated in rats after inducing burn. Seventy-two male Wistar Furth rats were equally divided into four groups as follow: controls (CON), untreated burnwound rats (BURN), normal saline-treated burn-wound rats (BURN-NSS) and Aloe vera-treated burn-wound rats (BURNALOE). The animals in each group were equally subdi...

BACKGROUND Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the effect of Lithospermum officinale, silver sulfadiazine and alpha ointments on healing of burn wounds in rat. METHODS Ninety-five rats were divided into 5 groups. Group 1 just underwent burn injury, and groups 2-5 received alpha ointment, silver sulfadiazine ...