BACKGROUND Pseudomonas aeruginosa remains a leading cause of severe wound infection and mortality in burn patients. OBJECTIVES The current study aimed to determine the prevalence of Ambler class A and D β-lactamases among P. aeruginosa isolated from infected burn injuries in Tehran, Iran. PATIENTS AND METHODS Bacteriological samples were taken from burn patients with clinical symptoms of bu...

Despite the advancement in burn therapy in the last decades the treatment of burn wounds still remains a challenging task. Infection is still a common complication; while sepsis remains the leading cause of death in severe burns. The research guided integration of new and effective techniques in burn wound management is mandatory. Negative pressure wound therapy (NPWT) is an effective and widel...

Gender-related differences in immune responses to hemorrhage and sepsis have been described. However, most trauma studies continue to limit experimental models to males to avoid the variable responses associated with hormonal fluctuation in proestrus/estrus females. In the present study, male and female (either diestrus or proestrus/estrus) Sprague-Dawley rats (250-325 g) were given a third-deg...

BACKGROUND Scarring is a major source of morbidity in patients with burns. Burn scars are difficult to treat and are among the worst scars seen in clinical medicine. Fractional laser resurfacing is a promising treatment option because of its unique wound healing response and depth of penetration. OBJECTIVE To evaluate the efficacy of nonablative fractional resurfacing as a therapeutic option ...

The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...

The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...

OBJECTIVE An accurate knowledge of energy consumption in burn patients is a prerequisite for rational nutrition therapy. This study sought to create a formula that accounts for the metabolic characteristics of adult burn patients to accurately estimate energy consumption of patients with different areas and extents of burn and at different times after injury. METHODS Resting energy expenditur...

OBJECTIVE To better characterize national genital burns (GBs) characteristics using a large burn registry. We hypothesized that mortality and morbidity will be higher in patients with GBs. METHODS The National Burn Repository, a large North American registry of hospitalized burn patients, was queried for patients with GB. Burn characteristics and mechanism, demographics, mortality, and surgic...

A body of data supports the efficacy of hyperbaric oxygen (HBO2) therapy in the treatment of thermal burns, but the role of HBO2 in the treatment of burn injury remains a subject of controversy. The aim of this study was to evaluate possible positive effects of HBO2 on the experimental burn wound healing. Deep second degree burns were produced on the depilated backs of 70 male Wistar rats using...