A critical need exists for a robust method that enables early discrimination between superficial-partial and deep-partial thickness burn wounds. In this study, we report on the use of laser speckle imaging (LSI), a simple, non-invasive, optical imaging modality, to measure acute blood flow dynamics in a preclinical burn model. We used a heated brass comb to induce burns of varying severity to n...

BACKGROUND AND OBJECTIVES Despite advances, inappropriate analgesic treatment for burn patients is still seen. The objective of this review was to collect data on pain management in burn patients. CONTENT We reviewed the mechanisms of pain, burn patient assessment, as well as pharmacological and non-pharmacological treatment. CONCLUSION Pain management in burn patients is still a challenge ...

A burn injury triggers traumatic reactions characteristics of a stress. Here we investigated the early responses of prolactin (PRL), corticosterone (CS), and signal transducer and activator of transcription 5 (STAT5) in male Sprague-Dawley rats after burn injury. PRL and CS levels were determined in blood serum. STAT5 and phospho-STAT5 levels were determined in jejunum total protein extracts. T...

Burn wound healing is a complex and dynamic process that involves the interaction between different cell types and mediators. Neovascularization is an imperative stage of wound healing and consists of not only angiogenesis but also adult vasculogenesis. A superficial partial-thickness burn (SPTB) heals within 2 weeks without scarring. A deep partial-thickness burn (DPTB), conversely, requires 2...

The United States Army Institute of Surgical Research was asked to provide burn care assistance in June 1989 following the explosion of leaking methane/propane gas in the Central Soviet Union, which destroyed two passenger trains and injured 800 passengers. A 17-member burn team flew from San Antonio, Texas, to Ufa, USSR and assisted in the management of 150 burn patients in a general medical-s...

Professor Li Ao was one of the founders of Chinese burn medicine and one of the most renowned doctors and researchers of burns in China. He established one of the Chinese earliest special departments for burns at Third Military Medical University (TMMU) in 1958. To memorialize Professor Li Ao on his 100th birthday in 2017 and introduce our extensive experience, it is our honor to briefly review...

The survival rates for burn patients have improved substantially in the past few decades due to advances in modern medical care in specialized burn centers. Burn wound infections are one of the most important and potentially serious complications that occur in the acute period following injury. In addition to the nature and extent of the thermal injury influencing infections, the type and quant...

Background and objectives: Severe burn damage and its consequences are life threatening which can complicate patients’ health. Burn damage increases reactive oxygen species (ROS) generation which leads to severe damage to tissues and is implicated in burn shock. Some medicinal and traditional plants are considered as safe, natural and inexpensive sources for treatment of differ...

Burn-related injuries are a leading cause of morbidity and mortality in children. Burn injuries rank third among injury-related deaths in children aged 1 to 9 years. In 2001, there were more than 181,000 fireand burn-related injuries, more than 4200 hospitalizations, and 672 deaths in children aged 0 to 19 years in the United States. Pediatric patients and the elderly have the highest morbidity...

Burn-in (BI) for programmed Field Programmable Gate Arrays (FPGAs) is a growing concern in the space community. This application note addresses these concerns with regard to the Actel RT54SX-S and SX-A FPGA device families in an unprogrammed versus a programmed mode. This application note discusses the main differences between the architecture of the RT54SX-S and SX-A families and it describes ...