This article describes a rare clinical presentation of Burkitt’s lymphoma, an aggressive malignancy that presented as anterior mediastinal mass causing Pancoast syndrome in 39-year-old pregnant woman. The patient with respiratory distress, right upper limb monoparesis, significant weight loss, and multiple bilateral axillary cervical lymphadenopathies. Blood tests revealed non-regenerative anem...

Background: Paraneoplastic pemphigus is an autoimmune blistering skin disease associated with concurrent neoplasia that is rarely observed in veterinary medicine. Case description: This case report presents a ten-year-old female Labrador Retriever dog with generalized seborrhea and alopecic, crusting and ulcerative lesions in the periocular and perioral regions...

Canine lymphoma is the most common neoplasm of the hematopoietic system with the most frequently diagnosed malignancy. Also, dogs affected by T-cell lymphoma displayed a lower rate of complete chemotherapy response and have a high risk of death in the early stage of the disease. A 5-year-old male mixed dog was presented to the Small Animal Hospital, School of Veterinary Medicine, Shiraz Univers...

Introduction. ?Grey zone Lymphoma?? is associated with various entities. The last published classification of lymphoproliferative neoplasms includes mediastinal grey lymphoma. Precise diagnostic criteria are insufficient and establishing a diagnosis as complex deciding on treatment options. In this article pathologist hematologist discuss issues topic through case presentation literature review...

background: coffee is implicated in the susceptibility to several cancers. however, the association between coffee and lymphoma remains unclear. this meta-analysis aimed to assess quantitatively the association between coffee and the incidence of lymphoma. methods: a literature search was performed for cohort and case-control studies published using pubmed, cochrane, and embase databases. studi...

Lymphomas are a diverse and relatively common cancer type in the UK. Early diagnosis of lymphoma is vital for improving patient outcomes. The majority patients diagnosed with have life expectancy more than 5 years. Lymphoma treatments can long-term health consequences, history higher risk subsequently developing other cancers. More robust evidence early primary care has been published recent ye...

Currently lymphoma is mainly treated with combination chemotherapy, hematopoietic stem cell transplantation, immunotherapy, and new targeted therapy, but treatment-related drug resistance, recurrence, extranodal central infiltration, leukemic transformation are still clinical problems that need to be solved urgently. Studies have shown cytokines expressed varying degrees in patients, which sign...

The clinical and biological significance of programmed death-1 (PD-1) expression by B-lymphoma cells is largely unknown. Here, using multicolor immunofluorescent staining (MC-IF), we investigated PD-1 PD-L1 in PAX5+ (B-lymphoma), CD68+ (macrophage), or CD3+ (T-cell) formalin-fixed, paraffin-embedded samples 32 consecutive patients with de novo diffuse large B-cell lymphoma (DLBCL) treated ritux...