background: as the early and accurate diagnosis of all diseases, including skin disorders directly influences the duration of treatment and its costs, which may be a significant burden, it is very important for physicians to be familiar with all types of diseases, especially those with a higher incidence in population. considering that disease patterns vary from region to region and there is no...

background:  scabies is an ectoparasitic infection, which occurs because of direct skin-to skin contact. the ideal treatment modality is still unclear and further research on this topic is warranted. the aim of the study was to com­pare the efficacy and safety of the topical scabicides: permethrin, crotamiton and sulfur ointment. methods: fifty four patients with diagnosed scabies were randomly...

Two major types of amyloidosis are primary amyloidosis or amyloid light chain amyloidosis and secondary amyloidosis. Although amyloidosis involves a variety of organ systems including skin, the occurrence of bullous skin lesions is rare. Little is known about the mechanism of blister formation. These blisters are often hemorrhagic and typically occur in the oral mucosa. Only a few case reports ...

Type VII collagen is an adhesion molecule of the extracellular matrix in epithelial basement membranes, and the main constituent of anchoring fibrils at the dermal-epidermal junction (DEJ). Autoimmunity against this protein is causing the rare organ-specific epidermolysis bullosa acquisita (EBA). EBA is a rare acquired, heterogeneous, chronic blistering disease of skin disease of skin and mucou...

treatment that allows pathogenic bacteria to multiply on the skin. Uncomplicated SSSIs can occur in the various layers of the skin (Figure 1) and in underlying tissue, and they are classified as primary infections, such as impetigo, or as secondary infections of existing lesions, which include atopic dermatitis, allergic contact dermatitis, and psoriasis. Infections occurring in lacerations, su...

Much of the original research on desmosomes and their biochemical components was through analysis of skin and mucous membranes. The identification of desmogleins 1 and 3, desmosomal adhesion glycoproteins, as targets in pemphigus, a fatal autoimmune blistering disease of the skin and mucous membranes, provided the first link between desmosomes, desmogleins, and human diseases. The clinical and ...

IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large series of patients with MMP. DESIGN Multicenter retrospective study. SETTING ...

the purpose of this study was to investigate the incidence of different types of skin diseases among 657 children who were seen during one year period (oct. 1971-setp. 1972) at the skin clinics of the isfahan university hospital. the incidence of different types of skin disease was compared with those of the adults. in general this study shows that in isfahan area the incidence of skin infectio...

conclusions several adverse effects are associated to anti-hcv drugs, hence appropriate skin care management and follow-up are very important. a careful anamnesis before the initiation of triple therapy is necessary to identify previous dermatological diseases that could increase skin adverse effects incidence. case presentation we report a case of a patient who discontinued telaprevir because ...