Transcription factors (TFs) alter gene expression in response to changes in the environment through sequence-specific interactions with the DNA. These interactions are best portrayed as a landscape of TF binding affinities. Current methods to study sequence-specific binding preferences suffer from limited dynamic range, sequence bias, lack of specificity and limited throughput. We have develope...

From a theoretical viewpoint, the (tree-)decomposition methods offer a good approach when the (tree)-width of constraint networks (CSPs) is small. In this case, they have often shown their practical interest. However, sometimes, a bad choice for the root cluster (a tree-decomposition is a tree of clusters) may drastically degrade the performance of the solving. In this paper, we highlight an ex...

Overshooting convective cloud Top (OT)-accompanied clouds can cause severe weather conditions, such as lightning, strong winds, and heavy rainfall. The distribution and behavior of OTs can affect regional and global climate systems. In this paper, we propose a new approach for OT detection by using machine learning methods with multiple infrared images and their derived features. Himawari-8 sat...

ATM Forum Document Number: BTD-TEST-TM-PERF.00.05 (96-0810R8) ********************************************************************************* Title: ATM Forum Performance Testing Specification Baseline Text ********************************************************************************* Abstract: This baseline document includes all text related to performance testing that has been agreed so ...

Histones are modified post-translationally, e.g. by methylation of lysine and arginine residues, and by phosphorylation of serine residues. These modifications regulate processes such as gene expression, DNA repair, and mitosis and meiosis. Recently, evidence has been provided that histones are also modified by covalent binding of the vitamin biotin. The aims of this study were to identify biot...

Biotinidase was identified in secretome analysis of thyroid cancer cell lines using proteomics. The goal of the current study was to analyze the expression of biotinidase in thyroid cancer tissues and fine needle aspiration (FNA) samples to evaluate its diagnostic and prognostic potential in thyroid cancer. Immunohistochemical analysis of biotinidase was carried out in 129 papillary thyroid can...

Abstract: Purpose: This study aims to determine whether there is a effect of maqashid sharia performance and islamic social reporting on tax aggressiveness with company size as moderating variabel. Research Methodology: research quantitative using secondary data in the form annual report banking Indonesia period 2016 2020 registed OJK. The technique samples were conducted purposive sampling obt...

This paper develops a nonlinear mid-fidelity aeroservoelastic model for smart rotor wind turbines and studies the turbulent load alleviation of with trailing edge flaps (TEFs) actuated by novel proportional-derivative model-free adaptive control (PD-MFAC) algorithm. contains structural tower blades represented geometrically non-linear composite beams an aerodynamic using vortex panel method cou...

Folding of DNA into chromatin is mediated by binding to histones such as H4; association of DNA with histones is regulated by covalent histone modifications, e.g. acetylation, methylation, and biotinylation. We sought to identify amino-acid residues that are biotinylated in histone H4, and to determine whether acetylation and methylation of histones affect biotinylation. Synthetic peptides span...