BACKGROUND Viral suppression and viral breakthrough impact the humoral immune response to HIV infection. We evaluated the impact of viral suppression and viral breakthrough on results obtained with two cross-sectional HIV incidence assays. METHODS All samples were collected from adults in the US who were HIV infected for >2 years. Samples were tested with the BED capture enzyme immunoassay (B...

OBJECTIVE Varicella breakthrough, the occurrence of varicella disease >42 days after vaccination, is indicative of vaccination failure. A sevenfold increased risk of breakthrough among vaccinated children with asthma was observed in a 1996 varicella outbreak in a child care center. More recent outbreak investigations have also identified age at vaccination as a potential risk factor for breakth...

â  a 56 year-old man with recurrent gastrointestinal bleeding is reported. the patient had constant crampy pain in his epigastrium, right upper quadrant and periumbilical area. upper-gastrointestinal endoscopy was normal. colonoscopy showed a soft-tissue mucoâ­sal lesion in the rectum which was determined to be a worm that extended into the lumen of the rectum with no bleeding. the pathology wa...

conclusion superselective tae for lgi bleeding has a high success and low complication rate. there are no statistical correlations between the clinical success rate and several variables, including embolic material, embolization site, and anticoagulant or antiplatelet medication. patients and methods fifty-two patients who underwent superselective tae for lgi bleeding between 2003 and 2011 were...

[no abstract available]

“Space drives,” “Warp drives,” and “Wormholes:” these concepts may sound like science fiction, but they are being written about in reputable journals. To assess the implications of these emerging prospects for future spaceflight, NASA supported the Breakthrough Propulsion Physics Project from 1996 through 2002. This project has three grand challenges: (1) Discover propulsion that eliminates the...

Treatment of chronic non-cancer pain with opioid therapy has escalated in recent years, resulting in exploding therapeutic use and misuse of prescription opioids and multiple adverse drug events. Breakthrough pain is defined as a transient exacerbation of pain experienced by individuals who have relatively stable and adequately controlled baseline cancer pain. Further, the definition of breakth...

[1] Tracer buoyancy has been shown to influence breakthrough from two-well tracer experiments conducted in porous media. Two-well tracer experiments are presented from fractured crystalline bedrock, in which the specific gravity of the tracer injectate varied from 1.0002 to 1.0133. Under the forced hydraulic conditions imposed, no difference in breakthrough was noted for the three experiments. ...

BACKGROUND The precision and limitations of ventricular pacemapping as a method to localize the site of earliest breakthrough of ventricular tachycardia (VT) were investigated in a canine model of experimental myocardial infarction. METHODS AND RESULTS Forty-one episodes of VT induced in 10 animals were mapped using a standard grid of 64 endocardial and epicardial bipolar electrodes to determ...