Single photon emission tomography SPECT has been used in nuclear medicine since the early 1960’s when Kuhl and Edwards developed a rectilinear scanning system for use in neuronuclear medicine. Tomography is now used extensi vely for diagnosis by ultrasound, x-ray CT scanning and magnetic resonance imaging. The improvement in quality of the images is due to the enhanced contrast produced by the ...

UNLABELLED The aim of this study was to evaluate impaired lung uptake of (123)I-metaiodobenzylguanidine ((123)I-MIBG) on SPECT, compared with perfusion SPECT and morphologic CT, in patients with pulmonary emphysema (PE). METHODS (123)I-MIBG SPECT was performed at 15 min and 4 h after intravenous injection of (123)I-MIBG in 36 PE patients with a history of smoking and variable-extent low-atten...

BACKGROUND SonoVue is a new microbubble contrast agent containing sulfur hexafluoride. We assessed the efficacy of SonoVue myocardial contrast echocardiography (MCE) to detect resting perfusion abnormalities. METHODS Nineteen adult patients with a wall motion abnormality in a screening echocardiogram were studied. Each patient received up to four bolus injections of 2.0 mL SonoVue (Bracco Dia...

Background: Pulmonary embolism (PE) is diagnosed either by ventilation/perfusion (V/Q) scintigraphy or pulmonary CT angiography. One of the imaging methods used in nuclear medicine is hybrid SPECT/CT scintigraphy. Objectives: The aim of this study was to evaluate the utility of SPECT/CT(Q) scintigraphy in the diagnosis of PE and to compare SPECT/ CT(Q) with planar(Q) and SPECT(Q) methods. Metho...

Introduction Dynamic contrast enhanced MRI (DCE-MRI) is used to characterize perfusion and extracellular volume in tumors through the tracer kinetic modeling of MRI contrast agents (typically Gd-DTPA). However, the parametric estimates resultant of DCE-MRI may be influenced by several confounding factors, including inter-compartmental water exchange [1]. In contrast to MRI contrast agents, radi...

UNLABELLED Cerebral amyloid angiopathy (CAA) is known to be an important cause of spontaneous cortical-subcortical intracranial hemorrhage in normotensive older persons. CAA can also manifest as leukoencephalopathy, brain atrophy, and ischemia secondary to hypoperfusion. Our goal was to verify cerebral hypoperfusion in patients with CAA using (99m)Tc-ethylcysteinate dimer ((99m)Tc-ECD) brain pe...

introduction: asymptomatic diabetic patients are at increased risk of cardiovascular complications. myocardial perfusion scan may be effective in risk evaluation in this population. methods: 106 asymptomatic diabetic patients (age: min: 37, max: 82, mean: 57.73±8.88), including 56 females (52.8%) and 50 males (47.2%) were enrolled in the study. myocardial perfusion scintigraphy was performed by...

introduction: motion of the patient during myocardial perfusion spect could potentially results in false perfusion defects. the effect of different reconstruction methods on these artifacts is not studied. clarification of the relation between the extent, severity and duration of motion with the resultant artifacts may be helpful in designing special soft wares for motion correction. this study...

Background: Pulmonary embolism (PE) is diagnosed either by ventilation/perfusion (V/Q) scintigraphy or pulmonary CT angiography. One of the imaging methods used in nuclear medicine is hybrid SPECT/CT scintigraphy. Objectives: The aim of this study was to evaluate the utility of SPECT/CT(Q) scintigraphy in the diagnosis of PE and to compare SPECT/ CT(Q) with planar(Q) and SPECT(Q) methods. Metho...