نتایج جستجو برای: brain inflammation
تعداد نتایج: 633631 فیلتر نتایج به سال:
While extensive studies report that neonatal hypoxia-ischemia (HI) induces long-term cognitive impairment via inflammatory responses in the brain, little is known about the role of early peripheral inflammation response in HI injury. Here we used a neonatal hypoxia rodent model by subjecting postnatal day 0 (P0d) rat pups to systemic hypoxia (3.5 h), a condition that is commonly seen in clinic ...
Worldwide pandemic of COVID-19 has resulted in various physiological manifestations mainly affecting the respiratory system and also nervous system. Inflammation, a hallmark symptom diseases links both neurodegenerative disorders. infection immune responses like cytokine chemokine production, even storms (in severe cases), which lead to inflammation. Parkinson’s Disease (PD), characterised by m...
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In the 1980s, authors developed enzyme immunoassay (EIA) system for mouse nerve growth factor (NGF) to clarify its important physiological roles. Our EIA was a new and powerful tool measurement of extremely low levels NGF in vitro vivo, it contributed investigation into regulatory mechanism synthesis. After that, we demonstrated that compounds with molecular weight, such as 4-methylcatechol, wh...
Objectives: Prenatal inflammation is a major factor associated with altered brain development in the newborn leading to neurodevelopmental diseases and enhanced susceptibility to brain damage occurring at a later stage. There is currently no treatment to alleviate the impact of prenatal inflammation on the development of the newborn. This is mainly due to the lack of non-invasive tools to detec...
Vascular endothelial growth factor (VEGF) is a vascular growth factor which induces angiogenesis (the development of new blood vessels), vascular permeability, and inflammation. In brain, receptors for VEGF have been localized to vascular endothelium, neurons, and glia. VEGF is upregulated after hypoxic injury to the brain, which can occur during cerebral ischemia or high-altitude edema, and ha...
chronic obstructive pulmonary disease (copd) is a condition associated with inflammation in lungs and airways. the impacts of inflammatory process is not limited to respiratory system but extend to extrapulmonary organs with resultant complications involving endocrine, metabolic and cardiovascular systems. the extent and severity of inflammation may be partly estimated by serum measurement of s...
A wide range of inflammatory mediators has been demonstrated in the Alzheimer’s disease (AD) brain during the past 15 years (for previous reviews, see [6, 279,298,340,343]). Questions nonetheless remain, including even the designation of AD inflammatory mechanisms as a true inflammatory response. Like multiple sclerosis, the cardinal signs of peripheral inflammation, the “rubor et tumor cum cal...
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