mone deficiencies). Radiation therapy greatly increases the lifelong risk of secondary malignant neoplasms (glioblastoma multiforme, malignant astrocytoma, meningioma, bone and soft-tissue sarcoma, and malignant melanoma) in children with TRB who are already predisposed to secondary cancers owing to their germline RB1 mutations. Treatment of TRB using the Toronto Protocol and intrathecal topote...

Adenoid cystic carcinoma (ACC) is a relatively rare epithelial tumor of the salivary glands that accounts for approximately 5 to 10% of all salivary gland neoplasms. The typical clinical and pathological findings of this tumor include slow indolent growth, common local recurrence, and late distant metastasis to lung, brain, bone, liver, thyroid, and spleen. We report a 52-year-old female patien...

Neurofibromatosis type 1 (NF1) and AIDS are risk factors for the development of malignant neoplasms, including hematological malignancies, such as non-Hodgkin lymphoma. NF1 is an autosomal dominant disease that primarily manifests as café-au-lait spots, dermal neurofibromas, axillary and/or inguinal ephelides or freckles, plexiform neurofibromas, Lisch nodules, and bone deformities. In this rep...

Background Aims: Diseases of the oral cavity are heterogenous regarding their etiology, pathogenesis, histogenesis and clinical outcomes. The aim this study was to examine frequency diseases encountered in our experience.
 Methods: archives pathology at Jordan University Hospital were retrospectively searched for specimens from 2013–2020. Fisher’s exact test performed statistical differenc...

Carcinoid tumours occur predominantly in the gastrointestinal tract and bronchial system of the lungs, but they can originate in less common anatomical sites such as the testes, which accounts for <1% of all testicular neoplasms. Carcinoid tumour is a rare and indolent neoplasm with the potential for distant metastasis. We report on a man with metastatic right testicular carcinoid tumour who ha...

In general , meningiomas are slowly growing benign neoplasms originating from specialized meningothelial cells in arachnoid granulation, but have a tendency to be locally invasive and recurrent. Meningiomas very rarely metastasize outside the nervous system, occurring in less than 0.1 %. We report the CT and MR findings of a case of a solitary benign syncytial meningioma showing recurrent multi...

Pulmonary hamartomas are benign tumors, which represent abnormal mixture of fibrous connective tissue, hyaline cartilage, fat and bone as well as bronchial epithelial cells. Differential diagnosis of tuberculoma, malignant neoplasms and hamartoma is necessary. We present the tuberculosis patient with pulmonary hamartoma mimicking lung tuberculoma. The uncorrected diagnosis of tuberculoma was ma...

Two cases of acute monarthritis secondary to asymptomatic renal cell carcinoma are described. This association has not previously been reported. The patients were initially thought to have a septic arthritis, but hot spots were seen on isotope bone scans and biopsy samples showed secondary neoplasms, which were later confirmed to be a result of renal cell carcinomas. The value of cytological ex...

Chordomas are rare neoplasms arising from notochordal remnants and may develop anywhere in the body while the most common anatomic site is the sacrococcygeal area. The most effective treatment of chordoma is surgery. Chordomas rarely metastasize to lung, bone, soft tissue, liver, lymph nodes, and skin. However, there is currently no standard systemic treatment for advanced stage chordoma. Here,...