Mycobacterium lepraemurium cells were found to multiply in normal mouse peritoneal-derived and bone marrow-derived macrophages in vitro. Whereas activated peritoneal-derived macrophages demonstrated marked bacteriostasis for M. lepraemurium, significant bactericidal activity was exhibited by activated bone marrow-derived macrophages. However, only a small proportion of the bacteria were killed ...

  Background and Objectives: Bone marrow necrosis (BMN) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. This study was performed to identify frequency and the underlying associated diseases of marrow necrosis. Materials and Methods: In this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the Pathology ...

Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. Metastatic diseases were found in 69% of patients in a reported series but the incidence of bone marrow involvement is unclear. We report a rare case of a 25-years-old Moroccan woman with unsuspected primary splenic angiosarcoma revealed by bone marrow metastasis. She presented with serious anemi...

Bone scintigraphy has some limitations in detecting bone lesions at the time of diagnosis since Tc99m MDP scintigraphy does not trace lesions lacking osteoblastic activity3. Tc99m Sestamibi (MIBI) has been proposed as a potential tracer in patients with multiple myeloma, as its increased uptake in the bone marrow has been reported as an indicator of myeloma activity4. It has been suggested to b...

PURPOSE Neovascular remodeling (NVR), the progression of small capillaries into large-caliber arterioles with perivascular fibrosis, represents a major therapeutic challenge in neovascular age-related macular degeneration (AMD). Neovascular remodeling occurs after laser-induced choroidal neovascularization (CNV) in aged but not young mice. Additionally, bone marrow-derived cells, including macr...

Objective: Our objective was to delineate the role of Ccr6 in atherogenesis in the apolipoprotein E–deficient (ApoE / ) mouse model of atherosclerosis. Methods and Results: Both Ccr6 and Ccl20 are expressed in atherosclerotic aorta from ApoE / mice. Aortic lesion area in Ccr6 / ApoE / mice was 40% and 30% smaller than in Ccr6 / ApoE / mice at 16 and 24 weeks of age, respectively. Transplantatio...

A 71-year-old woman presented with a 2-month history of progressive exophthalmos. Magnetic resonance imaging revealed a tumor occupying the right frontal sinus that compressed the right orbit and eye ball. The tumor was resected through a right frontal craniotomy. The pathologic diagnosis was leiomyoma and similar to the histologic diagnosis of a uterine leiomyoma resected 4 years earlier. We s...

hematopoietic stem/progenitor cells (hspcs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. interacting factors such as stromal derived factor-1/cxcr4, very late antigen-4/vascular cell adhesion molecule-1, lymphocyte function-associated antigen-1/ intercellular adhesion molec...

conclusions the results of this study showed that the meticulous microsurgical nerve repair, which was performed using the vein tubulization induced significantly better sciatic nerve regeneration. however, the addition of bone marrow mesenchymal stem cell to vein conduit failed to promote any significant changes in regeneration outcome. results all animals tolerated the surgical procedures and...

background: the purpose of this study was to find the accurate absorbed dose in the femur bone marrow during the x-ray radiography for constant mas and aec techniques. materials and methods: the dosxyznrc was used to simulate radiation doses in two human femurs during diagnostic radiography. egsnrc phantoms produced from actual ct images of human femurs were modified by adding seven micrometre ...