The objects of this study were to determine the rate of complications associated with Intra Cortical Bone Fixation Screws for Inter-maxillary fixation (IMF) and as a possible alternative to Arch-Bars in patients with un-displaced mandibular fractures. A descriptive case series study involving 25 adult patients (age range: 16-60 years) and requiring intra cortical bone fixation screws IMF was co...

Acute kidney injury (AKI) is a frequent clinical problem with a high mortality rate, generally caused by ischemic insults. Nevertheless, the kidney has a remarkably high capacity to regenerate after ischemic injury. Tubular cells can restore renal function by proliferation and dedifferentiation into a mesenchymal cell type, but also stem cells residing in bone marrow may contribute. We compiled...

Adiponectin is a multifunctional cytokine that has a role in regulating inflammation. Here we determined whether adiponectin modulates ischemic acute kidney injury. Compared with wild-type mice, adiponectin-knockout mice were found to have lower serum creatinine and less tubular damage or apoptosis following ischemia/reperfusion injury. This latter process was associated with decreased Bax and ...

Bone repair is a specialized type of wound repair controlled by complex multi-factorial events. The nervous system is recognized as one of the key regulators of bone mass, thereby suggesting a role for neuronal pathways in bone homeostasis. However, in the context of bone injury and repair, little is known on the interplay between the nervous system and bone. Here, we addressed the neuropeptide...

BACKGROUND To determine if exogenously injected bone marrow derived platelet-rich plasma (PRP) plus bone morphogenetic protein (BMP)-2 could accelerate the healing of bone-tendon junction injuries and increase the junction holding strength during the early regeneration period. METHODS A direct injury model of the bone-tendon junction was made using an Achilles tendon-calcaneus bone junction i...

Better understanding of bone growth and regeneration mechanisms within periosteal tissues will improve understanding of bone physiology and pathology. Macrophage contributions to bone biology and repair have been established but specific investigation of periosteal macrophages has not been undertaken. We used an immunohistochemistry approach to characterize macrophages in growing murine bone an...

We report the first case of dislocation of the symphysis between the great cornu and the body of the hyoid bone following strangulation in survivors. The present paper presents a rare case of injury to the hyoid bone and reviews the current knowledge on hyoid bone injuries in survivors.

Of ten thousand patients seen in the Orthopaedic Department of the Middlesbrough General Hospital, about one thousand are sportsmen, and overall the majority suffer an injury or disease of the collagen tissues with or without bone involvement. An important factor in soft-tissue lesions is the bio-feedback neurological mechanisms controlling joint movement, bone and muscle growth, and calcificat...

STUDY DESIGN Retrospective study. PURPOSE To compare intraoperative endplate injury cases and no injury cases in consecutive series and to identify predisposing factors for intraoperative endplate injury. OVERVIEW OF LITERATURE Unintended endplate violation and subsequent cage subsidence is an intraoperative complication of extreme lateral interbody fusion (XLIF). It is still unknown whethe...

Objectives: The study aimed to identify the Kaplan fiber (KF) complex, focusing on condylar strap (CS) which are straps lateral aspect of knee related iliotibital magnetic resonance imaging (MRI) knees performed for acute anterior cruciate ligament (ACL) injury, measure distances insertion from joint line, and injuries these structures. Material Methods: Retrospective analysis 134 MRIs with ACL...