Core body temperature is predominantly modulated by endogenous and exogenous components. In the present study we tested whether these two components can be reliably assessed in a protocol which lasts for only 120 h. In this so-called forced desynchrony protocol, 12 healthy male subjects (age 23.7 +/- 1.4 y) were subjected one by one to an artificial light/dark cycle of 20 h (10 lux vs. darkness...

obesity is characterized as a state of systemic low-grade inflammation suggesting a link between metabolism and immune function. obesity has been shown to predispose individuals to an increased risk of many diseases.since 1980s, a threefold increase in obesity has been reported in much of the world.obesity is a result of energy imbalance. one of the components that control energy balance is adi...

The Saccharomyces cerevisiae genes KAR1 and CDC31 are required for the initial stages of spindle pole body (SPB) duplication in yeast. The Cdc31 protein is most related to caltractin/centrin, a calcium-binding protein present in microtubule organizing centers in many organisms. Because of a variety of genetic interactions between CDC31 and KAR1 (Vallen, E. A., W. Ho. M. Winey, and M. D. Rose. 1...

The basal body shares similar architecture with centrioles in animals and is involved in nucleating flagellar axonemal microtubules in flagellated eukaryotes. The early-branching Trypanosoma brucei possesses a motile flagellum nucleated from the basal body that consists of a mature basal body and an adjacent pro-basal body. Little is known about the basal body proteome and its roles in basal bo...

Working in the framework of the ab−initio no-core shell model, we derive two-body effective interactions microscopically for specific harmonic-oscillator basis spaces from the realistic Argonne V 8 ′ nucleon-nucleon potential. However, our two-body effective interaction is only the dominant part of the A−body (A ≥ 3) effective interaction, which also contains three-, four-and, in general, up to...

The Saccharomyces cerevisiae genes KAR/ and CDC31 are required for the initial stages of spindie pole body (SPB) duplication in yeast. The Cdc31 protein is most related to caltractin/centrin, a calciumbinding protein present in microtubule organizing centers in many organisms. Because of a variety of genetic interactions between CDC31 and KARl (VaUen, E. A., W. Ho, M. Winey, and M. D. Rose. 199...