Epithelial to mesenchymal transition (EMT) is a process in which fully differentiated epithelial cells lose many of their epithelial characteristics and adopt features typical of mesenchymal cells, thus allowing cells to become migratory and invasive. EMT is a critical process in development and its role in cancer and fibrosis is becoming increasingly recognised. It is also becoming apparent th...

In an effort to define the roles of bone morphogenic proteins (BMPs) and fibroblast growth factors (FGFs) during chick limb development more closely, we have implanted beads impregnated with these growth factors into chick limb buds between stages 20 and 26. Embryos were sacrificed at the time the bone chondrocyte condensations first appear (stages 27-28). Implantation of beads containing BMPs ...

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Bone morphogenic proteins (BMPs) are universal regulators of animal development. We report the identification and cloning of the BMP type II receptor (BMPR-II), a missing component of this receptor system in vertebrates. BMPR-II is a transmembrane serine/threonine kinase that binds BMP-2 and BMP-7 in association with multiple type I receptors, including BMPR-IA/Brk1, BMPR-IB, and ActR-I, which ...

Ammonia accumulation in biogas plants reactors is becoming more frequently encountered, resulting reduced methane (CH4) production. toxicity occurs when N-rich substrates represent a significant part of the plant’s feedstock. The aim this study was to develop an estimation method for effect ammonia on CH4 production plants. Two periods where plant operated at 3200 mg·L−1 (1st period) and 4400 (...

-The concentration of 5-fluorouracil (FU) in thoracic-duct lymph, portalvein blood and peripheral arterial blood of beagle dogs was greater after administration into the submucosa of the stomach than after the bolus i.v. injection. The concentration of FU in thoracic-duct lymph, portal-vein blood and arterial blood was least following administration into the lumen of the stomach. The total FU r...

The latest research on stormwater practices and their construction indicates that innovative construction methods can reduce soil compaction and enhance exfiltration from bioretention cells and permeable pavement. In this publication, we summarize the current research and describe construction methods that developers can use to more effectively meet the goals of low impact development and storm...

Bone morphogenetic proteins (BMPs) and their receptors (BMPRs) are now known to have important roles in mammalian ovarian folliculogenesis. This study determined the expression of the mRNA encoding for BMPs and their receptors in the chicken ovary and explored possible roles for them. The expression of the mRNA for BMP-2, -4, -6, -7, and BMPR-IA, -IB, and -II was determined and quantified by a ...