Viscosity is a fundamental physical parameter that influences diffusion in biological processes. The distribution of intracellular viscosity is highly heterogeneous, and it is challenging to obtain a full map of cellular viscosity with detailed organelle information. In this work, we report 1 as the first fluorescent viscosity probe which is able to quantitatively map cellular viscosity with de...

The viscosity of the blood is expressed in this paper in terms of the coefficient K, obtained by calculation from the following known factors: the quantity of blood collected during a definite period, its specific gravity, the blood pressure, and the length and internal diameter of the capillary tube through which the blood is allowed to flow. When this coefficient has been compared with K for ...

INTRODUCTION This paper represents the numerical simulation of blood flow in the circle of Willis (CoW). Circle of Willis is responsible for the oxygenated blood distribution into the cerebral mass. To investigate the blood behavior, two Newtonian and non-Newtonian viscosity models were considered and the results were compared under steady state conditions. METHODS Methodologically, the arter...

Observations were made on an isolated hind leg preparation of dogs, perfused with blood and various homogeneous perfusates. A wide range of intravascular pressures were used while a constant arteriovenous pressure gradient was maintained. It was found that parallel increases in arterial and venous pressures result in a reduction in resistance to blood flow. A similar change in resistance is obs...

PURPOSE To investigate material density, flow, and viscosity effects on microsphere distribution within an in vitro model designed to simulate hepatic arteries. MATERIALS AND METHODS A vascular flow model was used to compare distribution of glass and resin surrogates in a clinically derived flow range (60-120 mL/min). Blood-mimicking fluid (BMF) composed of glycerol and water (20%-50% vol/vol...

In complex emulsions, viscosity or viscosity-associated sensory attributes such as creaminess are important for quality assessment and product differentiation. Two sets of emulsions with fat or locust bean gum content being varied at seven levels were developed; the two emulsions at each level had similar apparent viscosity. Additionally, sugar concentration was kept constant either with respec...

• Changes in vascular tone and pressure gradients have been established as important factors in the control of regional blood flow, but the influence of varied physical states of the perfusing blood is less clear. In a hemodynamic evaluation of shock, Seligman indicated that enhanced blood viscosity promoted the onset of irreversibility, presumably through an effect on flow. More recently Richa...

The reversible aggregation of red blood cells (RBC) into linear and three-dimensional structures continues to be of basic science and clinical interest: RBC aggregation affects low shear blood viscosity and microvascular flow dynamics, and can be markedly enhanced in several clinical states. Until fairly recently, most research efforts were focused on relations between suspending medium composi...

Classic features of polycystic ovary syndrome (PCOS) include derangement of metabolic and cardiovascular health, and vascular dysfunction is commonly reported. These comorbidities indicate impaired blood flow; however, other than limited reports of increased plasma viscosity, surprisingly little is known regarding the physical properties of blood in PCOS. We aimed to investigate whether haemorh...

During the coagulation process, blood changes from a liquid to a solid gel phase. These changes are reflected by changes in blood viscosity; however, blood viscosity at different shear rates (SR) has not been previously explored during the coagulation process. In this study, we investigated the viscosity changes of whole blood in 10 subjects with a normal coagulation profile, using a cone-on-pl...