A report of accidental poisoning of goats and cattle with the fertilizer, urea (46% Nitrogen) is made. All the fifteen goats IlJ1d five cattle involved in the intoxication eventually died. The clinical symptoms and pathological lesions were similar in both goats and cattle. There was a significant elevation of the blood urea nitrogen values in both cattle and goats; average for cattle being 39m...

Perchlorate (ClO4 (-)), an oxidizing agent, is a ubiquitous environmental pollutant. Several studies have investigated its thyroid hormone disrupting properties. Its associations with other biological measures are largely unknown. This study, combining 2005-2008 National Health and Nutrition Examination Surveys, investigated associations between urinary perchlorate and biomarkers of iron homeos...

Intracellular hydration may play a role in the regulation of protein and nitrogen metabolism. The hepatic removal of nitrogen by urea synthesis has a key regulatory role in nitrogen balance. The purpose of the present study was to establish the acute effects of dehydration on the hepatic kinetics of urea synthesis, quantified by functional hepatic nitrogen clearance (FHNC), in healthy volunteer...

In an earlier publication’ dealing with a micro method for the estimation of urea in blood, I also described a micro method for the estimation of ammonia in blood and in organic secretions. For the determination of the ammonia two analyses are made; in the first the total urea plus ammonia is determined; and in the second the urea alone after the ammonia has been removed by evaporating the bloo...

We developed a new technique that monitors metabolic competency in female heterozygotes for ornithine transcarbamylase deficiency (OTCD). The method uses mass spectrometry to measure conversion of 15 NH 4 Cl to [ 15 N]urea and [515 N]glutamine following an oral load of 15 NH 4 Cl. We found that heterozygotes converted significantly less NH 3 nitrogen to urea, with this difference being particul...

Nitrogen absorption from the large intestine, largely as ammonia and possibly as amino acids (AAs), is generally thought to be of little nutritional value to nonruminant animals and humans. Ammonia-nitrogen absorbed from the large intestine, however, may be recycled into the small intestine as urea and incorporated into microbial AAs, which may then be used by the host. A cecal infusion study w...

CONSTANT PROBLEM lli the hospital climiical laboratory is the emergency order which arrives with great regularity after the routine mu of a particular analysis has been finished. With automatiomi the problem has increased, particularly in laboratories where one automatic instrument is used for several different procedures in turii. There are three possible solutions. One is to perforni the test...

Nitrogen absorption from the large intestine, largely as ammonia and possibly as amino acids (AAs), is generally thought to be of little nutritional value to nonruminant animals and humans. Ammonia-nitrogen absorbed from the large intestine, however, may be recycled into the small intestine as urea and incorporated into microbial AAs, whichmay then be used by the host. A cecal infusion study wa...