Introduction: Vitamin D fulfills its crucial role in cell proliferation and death through signal transduction into the nucleus by vitamin D receptor (VDR). Recent studies have depicted the association between VDR gene polymorphisms and different cancers, including breast cancer. This study attempted to consider the relationship between VDR gene polymorphisms and breast cancer risk among women i...

BACKGROUND An association between the ABO groups and pancreatic cancer has been shown previously, group A being significantly commoner in affected patients. We conducted the present study to investigate the prognostic effect of ABO blood group on overall survival of pancreas cancer patients. METHODS Patients who were diagnosed between 2005 and 2010 with pancreas cancer at Ankara Numune Educat...

BACKGROUND There is a large amount of evidence that the ABO blood group system may play a role in disease etiology. A relationship between ABO and Rhesus blood groups and cancer risk has been demonstrated in a number of studies. However, in relation to gynecological malignancies, these findings are inconsistent and contradictory. AIM To perform a case-control study for analysis of the distrib...

Objective(s): Breast cancer is the most common cancer in women. Every year, one million new cases are reported worldwide, representing 18% of the total number of cancer in women. Hereditary BRCA1 and BRCA2 mutations account for about 60% of inherited breast cancer and are the only known causes of hereditary breast cancer syndrome. The aim of this study was to determine the frequency of BRCA2 (e...

Owing to aging populations, the prevalence of hypertension and associated cardiovascular events has been increasing worldwide. The morbidity mortality due cancer have also with populations. Several small-molecule inhibitors used in therapy, which a positive impact on prognosis survival patients cancer. Consequently, number survivors rapidly increasing. Anticancer including vascular endothelial ...

Autologous Active Specific Immunotherapy (AASI) is a type of immunotherapy that targets complementary autoantibodies which suppress the specific immune response using anti-idiotypic antibodies. AASI entails removing cells (dendritic cells) from patient's blood and subjecting them in lab setting to particular tumour antigen (proteins detected on surface cancer cells). personalized treatment appr...

Introduction: Cancer is, in essence, a genetic disease and is the second leading cause of death globally. Fortunately, many common types of cancer are treatable if detected early and of course there are many medications and treatments available today. Among the new methods to treat cancer, radiotherapy seems to be hopeful in patients with malignancies. This work investigates th...

Onco-hypertension is an emerging field investigating the relationship between hypertension and cancer. This paper details one part of this relationship—the effect anti-cancer agents on blood pressure. We review evidence linking targeted therapies, immunotherapy, traditional chemotherapies, hormonal with hypertension. Proposed pathophysiological mechanisms vary by drug but include endothelial dy...

background: cancer has the highest disease-related mortality rate in iran. reduced activity of paraoxonase reported in patients with cancer may be due to a reduction in its antioxidant properties and a subsequent increased risk of developing cancer. we aimed to assess antioxidant and oxidative status in patients with cancer through measuring the activity of pon1 as an antioxidant enzyme and det...