نتایج جستجو برای: bladder cancer cell line 5637

تعداد نتایج: 2636310  

Journal: :Carcinogenesis 2008
Dong-Il Kim Se-Jung Lee Soo-Bok Lee Keerang Park Wun-Jae Kim Sung-Kwon Moon

Naringin, an active flavonoid found in citrus fruit extracts, has pharmacological utility. The present study identified a novel mechanism of the anticancer effects of naringin in urinary bladder cancer cells. Naringin treatment resulted in significant dose-dependent growth inhibition together with G(1)-phase cell-cycle arrest at a dose of 100 microM (the half maximal inhibitory concentration) i...

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2011
Atsunari Kawashima Masashi Nakayama Yoichi Kakuta Toyofumi Abe Koji Hatano Masatoshi Mukai Akira Nagahara Yasutomo Nakai Daizo Oka Hitoshi Takayama Toshiaki Yoshioka Yoshihiko Hoshida Hiroaki Itatani Kazuo Nishimura Norio Nonomura

Purpose: Chemoradiation therapy (CRT) is now widely recognized as bladder-preserving therapy for muscle-invasive bladder cancer (MIBC). However, some patients who fail CRT may miss the chance to be cured by cystectomy. Therefore, it is important to select patients with MIBC who are expected to have a good response to CRT. Several reports indicate that the excision repair cross-complementing gro...

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2017
Christopher R. Silvers Hiroshi Miyamoto Edward M. Messing George J. Netto Yi-Fen Lee

The mechanisms of bladder cancer progression are unknown, and new treatments and biomarkers are needed. Patient urinary extracellular vesicles (EVs) derive in part from bladder cancer cells and contain a specific protein cargo which may provide information about the disease. We conducted a proteomics study comparing EVs from the muscle-invasive bladder cancer (MIBC) cell line TCCSUP to EVs from...

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2017
Eu Chang Hwang Seung Il Jung Hyun-Ju Lee Je-Jung Lee Dong Deuk Kwon

BACKGROUND In order to induce a potent cytotoxic T lymphocyte (CTL) response in dendritic cell (DC)-based immunotherapy for bladder cancer, various tumor antigens can be loaded onto DCs. OBJECTIVE The aim of this study was to establish a method of immunotherapy for male patients with non-muscle invasive bladder cancer (NMIBC), using bladder cancer-specific CTLs generated in vitro by DCs. MA...

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2011
Liansheng Ren

The inhibition effect of brazilin to human bladder tumor cell line T24 in vitro and in vivo was studied. The results of the in vitro experiments showed that brazilin has strong inhibition activity on the target cells. The inhibition ratio of 100 μg/mL brazilin and 100 μg/mL mitomycin to the target cells was 90.90 % and 63.24 % respectively, which showed that brazilin has higher inhibition activ...

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ژورنال: مجله علوم پزشکی رازی 2016
رشید شیخ احمد, محسن, سنجریان, فروغ, صابونی, فرزانه,

Background: Every year thousands of people die because of stomach cancer and brain tumors. N. sativa plant has thymoquinone and this compound may prevent cancer cell line growth in many types of cancer. The purpose of this study was to examine the possibility of inhibiting cell growth in human stomach gastric adenocarcinoma (AGS) and astrocytoma cell lines (AST) by N. sativa and N. arvensis ext...

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Journal: :nephro-urology monthly 0
pejman shadpour hasheminejad kidney center (hkc), hospital management research center (hmrc), iran university of medical sciences (iums), tehran, ir iran; hasheminejad kidney center (hkc), hospital management research center (hmrc), iran university of medical sciences (iums), tehran, ir iran. fax: +98-2188644447 maryam emami hasheminejad kidney center (hkc), iran university of medical sciences (iums), tehran, ir iran saeid haghdani hasheminejad kidney center (hkc), iran university of medical sciences (iums), tehran, ir iran

conclusions nbi cystoscopy improved the detection rate. although false positives were more common with nbi, this was not statistically significant. nbi found additional aggressive tumors, which underscores the impact of detection in eortc recurrence risk scoring. results fifty patients, aged 63.86 ± 10.05 years, were enrolled. the overall detection rate was 98.9% for nbi vs. 89.4% for wli (p = ...

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Journal: Iranian Journal of Blood and Cancer 2016
Afshin Almasi, Masoud Sadeghi, Mazaher Ramezani, Nima Naderi,

Background: Bladder cancer accounts for about 7% of all cancers among adults in Iran. We aimed to evaluate epidemiological and clinicopathological features of bladder cancer in Kermanshah province, west Iran. Methods: In a descriptive retrospective study, records of patients with bladder cancer referring to Imam Reza Hospital, Kermanshah city, Iran during 2011-2013 were analyzed. Sex, age, smo...

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Journal: :Memo – Magazine of European Medical Oncology 2022

Summary Although no game-changing studies in bladder cancer were presented this year at ASCO, we saw a series of interesting data including follow-up updates, exploratory analyses and promising results phase I/II trials. An up-date analysis the JAVELIN 100 Bladder study indicated benefit avelumab maintenance treatment irrespective response to platin-based first-line administration second-line t...

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2016
Joshua I. Warrick Vonn Walter Hironobu Yamashita Eunah Chung Lauren Shuman Vasty Osei Amponsa Zongyu Zheng Wilson Chan Tiffany L. Whitcomb Feng Yue Tejaswi Iyyanki Yuka I. Kawasawa Matthew Kaag Wansong Guo Jay D. Raman Joo-Seop Park David J. DeGraff

Discrete bladder cancer molecular subtypes exhibit differential clinical aggressiveness and therapeutic response, which may have significant implications for identifying novel treatments for this common malignancy. However, research is hindered by the lack of suitable models to study each subtype. To address this limitation, we classified bladder cancer cell lines into molecular subtypes using ...

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    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->