In medicinal chemistry nitrogen containing heterocycles are the most important compounds which show various biological activities. The cinnoline are nitrogenous derivatives and found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti tumor, antibacterial and antisecretory activity. We planned to synthesis new series of ...

In the study were presented data for comparison of antibacterial activities between long time stored acacia (Robinia pseudoacacia L.), multifloral and oak (Quercus spp.) honeydew honeys towards Staphylococcus aureus (ATCC 9144). The results showed that the antibacterial activity of oak honeydew and multifloral honeys was much higher in comparison with acacia honeys with the lowest antibacterial...

Solvent extracts from the carnivorous plant Dionaea muscipula (Venus flytrap) were prepared using eight different organic solvents, and examined for antibacterial activity against food-related pathogenic and putrefactive bacteria. All solvent extracts showed higher antibacterial activity against gram positive bacteria than against gram negative bacteria. The TLC-bioautography analysis of the ex...

A novel antibacterial peptide that shows antibacterial activity against Staphylococcus aureus was isolated from the hemolymph of the silkworm, Bombyx mori. The novel peptide consisted of 42 amino acids and was highly basic. This peptide indicated no significant similarity with other antibacterial peptides. The peptide showed antibacterial activity against several Gram-negative and -positive bac...

The objective of this work is to investigate the antibacterial activity of Artocarpus heterophyllus plant. The antibacterial activity of essential oil obtained from plant was examined. To evaluate the antibacterial activities of these extracts; their in vitro antibacterial activities were determined by disk diffusion testing and minimum inhibitory concentration (MIC). Escherichia coli, Pseudomo...

background & aim: the major aim of this study was to determine the antibacterial activity of the essential oils from five medicinal plants. experimental: the hydro-distillation essential oils from five plant species, including satureja bachtiarica, zataria multiflora, thymus daenensis, thymus carmanicus, and ziziphora tenuior (lamiaceae) which are endemic in iran. in-vitro antibacterial tes...

quinolones are broad-spectrum antibacterial agents.they have many clinical uses which are increasing.quinolones exert antibacterial activity primarily by inhibiting bacterial DNA gyrase.the inhibition of DNA gyrase by the quinolones are greatly influenced by the nature of the C-7 substituent on the quinolones molecule.substitution of bulky functional groupd is also possible in C-7 position.furt...

Background: Iran is a land of great heritage of ancient medical scholars. Herbal medicines, as a basement of treatment of diseases have been clearly described in the medical texts of these scholars including Rhazes, Avicenna, and others. Numerous plants are introduced in these texts to treat those diseases likely to be infective ones. Few attempts have been made to evaluate ethnopharmacological...

BACKGROUND Diseases caused by bacteria remain a major challenge globally and particularly in sub-Saharan Africa. The plants used in this study have been used in South Africa to treat helminth infections in livestock and humans. In a previous study we found a correlation between antifungal and anthelmintic activity in some cases. In this study we examined other potential uses of these thirteen p...