Background Effect of seasonal changes in human reproduction has been intensively researched. Some studies acknowledge influences of seasonal variation on natural conception, while others can not confirm them. The aim of this study was to investigate the effect of seasonal changes on different stages of assisted reproductive technology (ART) in Tehran. MaterialsAndMethods This study was carried ...

Background and aims: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system.The impact of the number of attacks on the disease is undeniable. The aim of this study was to analyze thenumber of attacks in these patients.Methods: In this descriptive-analytical study, the registered data of 1840 MS patients referred to the MS clinicof Ayatollah Kash...

We discuss the modeling of count data whose empirical distribution is both multi-modal and overdispersed, and propose the Hermite distribution with covariates introduced through the conditional mean. The model is readily estimated by maximum likelihood, and nests the Poisson model as a special case. The Hermite regression model is applied to data for the number of banking and currency crises in...

A new class of multivariate discrete distributions with binomial and multinomial marginals is studied. This class of distributions is obtained in a natural manner using probabilistic properties of the sampling model considered. Some possible applications in game theory, life testing and exceedance models for order statistics are discussed.

RNA sequencing (RNA-Seq) is the current method of choice for characterizing transcriptomes and quantifying gene expression changes. This next generation sequencing-based method provides unprecedented depth and resolution. The negative binomial (NB) probability distribution has been shown to be a useful model for frequencies of mapped RNA-Seq reads and consequently provides a basis for statistic...

Given the well known convergence difficulties in fitting log binomial regression with standard GLM software, we implement a direct solution via constrained optimization which avoids the circumventions found in the literature. The use of a log binomial model is motivated by our interest in directly estimating relative risks adjusted for confounders. A Bayesian log binomial regression model is al...

We consider multi-state capture-recapture-recovery data where observed individuals are recorded in a set of possible discrete states. Traditionally, the Arnason-Schwarz model has been fitted to such data where the state process is modeled as a first-order Markov chain, though second-order models have also been proposed and fitted to data. However, low-order Markov models may not accurately repr...

Mathematical models have been used to understand the transmission dynamics of infectious diseases and to assess the impact of intervention strategies. Traditional mathematical models usually assume a homogeneous mixing in the population, which is rarely the case in reality. Here, we construct a new transmission function by using as the probability density function a negative binomial distributi...