Background Dymista (MP29-02*) is a novel intranasal formulation of azelastine hydrochloride (AZE) and fluticasone propionate (FP) in an advanced delivery system with a welldocumented effect on allergic rhinitis. Its somewhat bitter taste is probably derived from AZE, a potent histamineH1-receptor antagonist. The taste is sometimes looked upon as a disadvantage. However, it might be that AZE ind...

In two studies, we investigated how bitter taste preferences might be associated with antisocial personality traits. Two US American community samples (total N = 953; mean age = 35.65 years; 48% females) self-reported their taste preferences using two complementary preference measures and answered a number of personality questionnaires assessing Machiavellianism, psychopathy, narcissism, everyd...

Ammonium sulfate fractionated proteins of bitter gourd (Momordica charantia) were precipitated using jack bean extract as a source of concanavalin A. Concanavalin A-bitter gourd peroxidase retained nearly 86% original activity. This complex was entrapped into calcium alginate-pectin gel. Entrapped concanavalin A-peroxidase complex retained 51% original activity. Soluble and immobilized peroxida...

Article: The bitter taste receptor agonist quinine reduces calorie intake and increases the postprandial release of cholecystokinin in healthy subjects CC This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproducti...

Bitter tastants are a potential new weight-loss treatment. This is noninvasive, easy approach, which should be received with considerable enthusiasm by the public. However, literature about bitter administration lacks consistency in methods and findings. We summarize how compound given based on: site of administration, best to use, at what timing respect meal. paper therefore fundamental step c...

The elderly population has experienced increased life expectancy as well as the increased incidence of gastric ulcers. The peels of fruits from Citrus aurantium L., popularly known in Brazil as orange bitter, are commonly used asatea form for the treatment of gastrointestinal tract disorders, such as ulcer and gastritis. We evaluated the healing effects of essential oil from the peels of Citrus...

Antinematodal efficacy of Saussurea lappa roots (Qust-e-Shereen) and anticestodal effect of Nigella sativa seeds (Kalonji) was studied in children infected naturally with the respective worms. The activities were judged on the basis of percentage reductions in the faecal eggs per gram (EPG) counts. The 50 mg/kg single dose of S. lappa and equivalent amount of its methanolic extract produced on ...