BACKGROUND Nonclinical studies indicate that the hormone relaxin is a good candidate for a safe cervical ripening agent that does not cause uterine contractions. METHODS This Phase II study (conducted November 2, 2005-October 20, 2006) was a randomised, double blind, placebo controlled trial testing 24-h intravenous infusion of serelaxin (recombinant human relaxin) or placebo for cervical rip...

labor is a physiological event involving a sequential, integrated set of changes within the myometrium, deciduas, and uterine cervix that occur gradually over a period of days to weeks. biochemical connective tissue changes in the uterine cervix appear to precede uterine contractions and cervical dilation, and all of these events usually occur before rupture of the fetal membranes. in other wor...

Castor oil was first noted to have oxytocic properties by ancient Egyptians. Derived from the castor plant Ricinus communis, castor oil may possess properties that are useful are in post-term pregnancies This study was performed at Khatam-Alanbia, hospital in shoushtar city in 1381.In this clinical trail 80 pregnant women, who had indication for induction of labor at term were randomly assigned...

Objective: To assess the diagnostic efficacy of Bishop Score and Transvaginal Ultrasonography (TVS) in predicting successful labor induction primigravida women a peri-urban population Islamabad. Additionally, study aimed to evaluate effectiveness combining predictions from both methods enhance accuracy induction. Methodology: A prospective comparative was conducted at Departments Obstetrics Gyn...

OBJECTIVE The aim of this analysis was to examine the management of cervix cancer in elderly patients referred for radiotherapy and the results of treatment in terms of overall survival (OS), relapse-free survival (RFS), and treatment-related toxicities. METHODS Patients were eligible if they were aged ≥75 years, newly diagnosed with cervix cancer and referred for radiotherapy as part of thei...