Hydrogen gas is a bioactive molecule that has a diversity of effects, including anti-apoptotic, anti-inflammatory and anti-oxidative properties; these overlap with the process of neuroprogression in major psychiatric disorders. Specifically, both bipolar disorder and schizophrenia are associated with increased oxidative and inflammatory stress. Moreover, lithium which is commonly administered f...

Tobacco use in mental health in general and bipolar disorder in particular remains disproportionally common, despite declining smoking rates in the community. Furthermore, interactions between tobacco use and mental health have been shown, indicating the outcomes for those with mental health disorders are impacted by tobacco use. Factors need to be explored and addressed to improve outcomes for...

background: anxiety disorders and substance abuse are commonest comorbidities among bipolar i disorder (bid) patients. this study investigated the prevalence of anxiety disorders among bid patients based on their dependency on opioid. methods: in this cross sectional study the bid patients in iranian hospital of psychiatry were divided into two 89-patient groups; one group was considered as opi...

BACKGROUND This study investigated the impact of comorbid obsessive-compulsive disorder (OCD) and four anxiety disorders [panic disorder (PD), agoraphobia, social anxiety disorder (SAD), and generalized anxiety disorder (GAD)] on the clinical outcomes of bipolar disorder. METHODS This study analysed data of 174 patients with bipolar I disorder who participated in the prospective observational...

BACKGROUND The aim of this study was to determine the risk for Bipolar Disorder (BD) in Wilson's disease (WD) and to measure the impaired Quality of Life (QL) in BD with WD using standardized psychiatric diagnostic tools and a case control design. METHODS This was a case control study. The cases were 23 consecutive patients with WD treated at the University Hospital in Cagliari, Italy, and th...

We previously demonstrated that patients with schizophrenia or bipolar disorder and their relatives are overrepresented in creative occupations. Here, we use a new dataset with a considerably larger sample of patients (n = 1,173,763) to survey other psychiatric diagnoses and to validate previous findings. The specific aims of this study were to i) investigate if creativity is associated with al...

BACKGROUND Recent studies have demonstrated high rates of psychopathology in the offspring of parents with bipolar disorder. The aim of this study was to identify psychiatric diagnoses in a sample of children of bipolar parents. METHOD This case series comprised 35 children and adolescents aged 6 to 17 years, with a mean age of 12.5 ± 2.9 years (20 males and 15 females), who had at least one ...

Previous studies showed that psychiatric disorders such as major depression, bipolar disorders, and alcohol misuse are associated with an increased risk of ischemic stroke. However, the link between psychiatric disorders and stroke in the young population is rarely investigated. Using the Taiwan National Health Insurance Research Database, 2063 young adults aged between 18 and 45 years with isc...

ôbjective: the mood disorder questionnaire (mdq) has been developed as a self-reporting, brief, and easy-to-use screening instrument to improve identification of bipolar mood disorders. the goals of the present study were to examine the prevalence of this disorder and interrelationship of its symptoms by factor analysis of mdq in a group of pregnant women in ïran. methods: ône thousand and eigh...

Bivalent cations play a lot of roles in human brain. Calcium, magnesium zinc ,copper and other cations are involved in normal functions of the brain .The most important mechanisms of action for cations are : modulation of the presynaptic release of some neuromediators , influence on neuronal ionic channels, induction of changes in some receptors activity, influence on the transporters of neurom...