Aggrecan, the most abundant extracellular proteoglycan in cartilage (~35 % by dry weight), plays a key role in the biophysical and biomechanical properties of cartilage. Here, we review several approaches based on atomic force microscopy (AFM) to probe the physical, mechanical, and structural properties of aggrecan at the molecular level. These approaches probe the response of aggrecan over a w...

Introduction. This review is intended to highlight and discuss discrepancies in the literature of the periodontal ligament's (PDL) mechanical properties and the various experimental approaches used to measure them. Methods. Searches were performed on biomechanical and orthodontic publications (in databases: Compendex, EMBASE, MEDLINE, PubMed, ScienceDirect, and Scopus). Results. The review reve...

Purpose. To evaluate the corneal biomechanical parameters in myopic and emmetropic eyes using Corneal Visualization Scheimpflug Technology (CorVis ST). Methods. 103 myopic and emmetropic eyes of 103 patients were examined. Corneal biomechanical parameters, axial length, and mean keratometry were measured using CorVis ST, IOL Master, and topography, respectively. Corneal biomechanical properties...

The invasive phenotype of glioma cells is thought to be responsible for recurrences. Ultrasmall Gd3+ chelate-coated gold nanoparticles interfere with capacities migrate and invade due induced changes in intrinsic biomechanical properties.

In type 1 diabetes, diabetic bone disease (DBD) is characterized by decreased bone mineral density, a state of low bone turnover and an increased risk of fracture. Animal models of DBD demonstrate that acquired alterations in trabecular and cortical bone microarchitecture contribute to decreased bone strength in diabetes. With anti-collagenolytic and anti-inflammatory properties, tetracycline d...

PURPOSE In recent years, the interest in corneal biomechanics has strongly increased. The material properties of the cornea determine its shape and therefore play an important role in corneal ectasia and related pathologies. This review addresses the molecular origin of biomechanical properties, models for their description, methods for their characterisation, techniques for their modification,...

background patients who have shoulder pain usually have compensatory or contributory deviation of shoulder motion during arm elevation. in the traditional scapulohumeral rhythm, the share of the acromioclavicular (ac) and the sternoclavicular (sc) joint movements and also the role of ac internal rotation angle are unknown. objectives the main purpose of this study was to measure and compare the...

PURPOSE To investigate the correlation coefficients between intraocular pressure (IOP) before and after adjusting for central corneal thickness (CCT) and corneal biomechanical properties. PATIENTS AND METHODS A total of 218 eyes of 218 patients with primary open-angle glaucoma (mean age =71.5 years; mean spherical equivalent =-0.51 D; mean deviation determined by Humphrey visual field analyze...

purpose: to compare outcomes of two techniques (anwar vs. melles) of deep anterior lamellar keratoplasty (dalk) in patients with keratoconus. methods: this randomized double-blind clinical trial was performed on 57 eyes of 57 patients with keratoconus. patients aged 20-35 years with a clinical diagnosis of keratoconus who were contact lens intolerant and had corrected distance visual acuity (cd...