Dielectrophoresis (DEP) is a physical effect that generates a force on polarisable particles experiencing a non-homogeneous electric field; studying the effect as a function of frequency allows the determination of the electrical properties of that particle, i.e., the electrical permittivity and conductivity. In the past, DEP-based techniques applied to the measurement of one or several cells a...

Large-scale microparticle arrays (LSMAs) are key for material science and bioengineering applications. However, previous approaches suffer from trade-offs between scalability, precision, specificity and versatility. Here, we present a porous microwell-based approach to create large-scale microparticle arrays with complex motifs. Microparticles are guided to and pushed into microwells by fluid f...

BACKGROUND The evaluation of the peritoneal transport characteristics is mandatory in peritoneal dialysis (PD) patients. This is usually performed in routine clinical practice with a peritoneal equilibration test (PET) using conventional dialysates, with low pH and high glucose degradation product (GDP) concentrations. An increasing proportion of patients are now treated with biocompatible dial...

We present a method to produce micropatterns of cells on tissue culture substrates. A network of deep elastomeric microchannels defining the desired pattern is sealed onto the surface of interest, and a protein template is created by injecting sub-milliliter quantities of protein solution into the microchannels. Protein adsorbs only on the areas that were exposed to the microflow. After the cha...

[*] Prof. F. G. Omenetto, P. Domachuk, J. Amsden, J. Bressner Department of Biomedical Engineering and Department of Physics Tufts University, 4 Colby Street Medford, MA 02155 (USA) E-mail: [email protected] S. T. Parker, Prof. J. A. Lewis Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-Champaign 1304 W...

This review of biocompatible lipophilic drug encapsulating and delivery systems entails the basics of colloidal drug delivery with special reference to oil-in-water microemulsion. The behaviour of the biocompatible systems, their formulation and ingredients, physicochemical properties, applications through different routes, advantages and restrictions therein have been presented. In vitro and i...

We report a simple, rapid approach to synthesize water-soluble and biocompatible fluorescent quantum dot (QD) micelles by encapsulation of monodisperse, hydrophobic QDs within surfactant/lipid micelles. Analyses of UV-vis and photo luminescence spectra, along with transmission electron microscopy, indicate that the water-soluble semiconductor QD micelles are monodisperse and retain the optical ...