نتایج جستجو برای: biliary tract injury
تعداد نتایج: 464092 فیلتر نتایج به سال:
Curative resection is the only treatment for biliary tract cancer that achieves long-term survival. However, patients with advanced biliary tract cancer have only a limited prognosis even after radical surgical resection. Thus, to improve the longterm results, the early detection of biliary tract cancer and subsequent cure seem to be essential. The purpose of this study was to review the litera...
Background: Biliary tract diseases in the elderly are common and representing particular both diagnostic and therapeutic problems. Endoscopic retrograde cholangiopancreatography (ERCP) is effective for the diagnosis and treatment of hepatobiliary and pancreatic diseases. Objective: To study the presentations of obstructive biliary disease, and the treatment outcome in elderly patients who under...
5-FU is the drug most frequently used to treat biliary tract cancer, while dihydropyrimidine dehydrogenase (DPD) is known to be a principal factor in 5-FU drug resistance. However, whether DPD activity and mRNA levels correlate with response to 5-FU is unknown for biliary tract cancers. The precise mechanism of DPD regulation also remains to be elucidated. In the present study, we quantitativel...
BACKGROUND The cystic dilatation of the biliary tract is a rare disease and uncertain origin. It is recognized more frequently in children; however, its incidence comes increasing in adults, representing 20% of the cases. AIM To evaluate morbimortality rates, evolution and handing of patients with cystic dilatation bile ducts in adults. METHODS Were evaluated, retrospectively, five adults w...
It is necessary to establish effective chemotherapy to improve the survival of patients with biliary tract cancer, because most of these patients are unsuitable candidates for surgery, and even patients undergoing curative surgery often have recurrence. Recently, the combination of cisplatin plus gemcitabine was reported to show survival benefits over gemcitabine alone in randomized clinical tr...
OBJECTIVES To describe the occurrence of pancreatic, biliary tract, and gallbladder cancers within the Alaska Native (AN) population. STUDY DESIGN Population-based analysis utilizing a tumor registry and comparative population data. METHODS Pancreaticobiliary cancers rates for AN people during 1973-2007 were determined from the Surveillance, Epidemiology, and End Results (SEER) AN Tumor Reg...
BACKGROUND The incidence of pancreatic or biliary tract cancer is increasing in our aging population, but little is known of treatment outcomes in elderly patients with pancreatic or biliary tract cancer. PATIENTS AND METHODS Patients with pancreatic or biliary tract cancer who received chemotherapy in our institute between September 2007 and August 2009 were retrospectively reviewed to compa...
OBJECTIVES This study investigated the association between cancer of the extrahepatic biliary tract and exposure to endocrine-disrupting compounds. METHODS Altogether 183 men with histologically confirmed carcinoma of the extrahepatic biliary tract and 1938 matched controls were interviewed between 1995 and 1997 in the frame of an international multicenter case-control study in six European c...
Primary Sclerosing Cholangitis as a Premalignant Biliary Tract Disease: Surveillance and Management.
Primary sclerosing cholangitis (PSC) is a premalignant biliary tract disease that confers a significant risk for the development of cholangiocarcinoma (CCA). The chronic biliary tract inflammation of PSC promotes pro-oncogenic processes such as cellular proliferation, induction of DNA damage, alterations of the extracellular matrix, and cholestasis. The diagnosis of malignancy in PSC can be cha...
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