In clinical studies of the metabolic behavior of radioactively labeled proteins, the turnover (biological half-life or degradation rate) is usually determined from serum (or plasma) concentration curves which entail multiple blood sampling. The amounts of retained isotope are customarily inferred (by difference) from the analyses of excreta obtained from complete 24-hour samples collected for a...

The TopCount Microplate Scintillation and Luminescence Counter has been widely used in biopharmaceutical assays involving both radionuclide and luminescence measurement. A new feature allows the use of TopCount for measuring a high energy beta emitter such as P by Cerenkov counting, a well-known measurement technique that has the main advantage of not requiring the addition of scintillation coc...

Radioimmunoassays for methotrexate are described, involving use of a rabbit antiserum to a conjugate of the drug and bovine serum albumin and the drug labeled with tritium, selenium-75, or iodine-125. Of the two gamma emitters, the 75Se-labeled drug was prepared by the Radiochemical Centre, Amersham, England and the 1251-labeled drug in the laboratory, by the Chloramine T iodination technique. ...

Radioimmunotherapy is a recently approved treatment modality for non-Hodgkin's lymphoma that enables physicians to target cytotoxic localized radiation to tumor sites without using external-beam sources. Because it uses a pure beta emitter for therapy, (90)Y ibritumomab tiuxetan can be safely and routinely administered in an outpatient procedure, with few discharge instructions, and minimal ris...

This paper will describe an active pixel CMOS-compatible imager aimed at high resolution still cameras. We will discuss pixel operation, column sense circuits, serial output, and show results from existing imagers. In this abstract, we show results from a prototype 640x480 imager with 5.9x5.9 μm2 pixels built in 0.8 μm double-poly CMOS with one additional base implant. Active Capacitor-coupled ...

Emitter geolocation using a single moving receiving-station is explored. We propose algorithms for transponder-aided geolocation of an emitting station where the transmitted waveform is either known or unknown a priori. The emitter position is estimated directly (in a single-step) from the received signal samples. Numerical examples are provided to illustrate the performance. The results are co...

Equations describing the high-frequency nonlinear behavior of common-emitter and differential-pair transconductance stages are derived. The equations show that transconductance stages using inductive degeneration are more linear than those using capacitive or resistive degeneration, and that the common-emitter transconductance stages are more linear than the differential-pair transconductance s...

In this paper, we investigate the energy spectrum and coherent dynamical process in a cavity-QED setup with moving emitter, which is subject to harmonic potential. We find that vibration of emitter will induce effective Kerr optomechanical interactions. generalize Bogliubov operators approach dealt quantum Rabi model, our cavity-emitter-vibration system obtain exactly. With assistance approach,...