The reactivity of 2-benzyl-1,2,3-triazole in palladium-catalyzed direct arylation was studied. reaction conditions for the selective synthesis 2-benzyl-4-aryl-1,2,3-triazoles moderate to high yields using phosphine-free Pd(OAc)2 catalyst and inexpensive KOAc base have been found. Then, from these 4-aryl-1,2,3-triazoles, C?H bond functionalization C5-position allowed corresponding 4,5-diarylated...

a few analogues of atevirdine or 1-[(5-methoxyindol-2-yl) carbonyl]-4-[3- (ethylamino)-2-pyridyl] piperazine – an anti-hiv belonging to non-nucleoside reverse transcriptase inhibitors were synthesized and evaluated for anti-hiv activity. replacement of indolyl moiety with 2-alkylthio-1-benzyl-5-imidazolyl substituent afforded 1-[2-(alkylthio-1-benzyl-5-imidazolyl) carbonyl]-4-[3-(isopropylamino...

Treatment of substituted benzyl alcohols with tosyl chloride resulted in the formation of the corresponding chlorides, not the usual tosylates. A series of experiments demonstrated that it was possible to predict whether chlorination or tosylation would occur for substituted benzyl alcohols and pyridine methanols. Treatment of electron withdrawing group-substituted benzyl alcohols with tosyl ch...

The title compound, C15H15N, represents an E isomer. The mol-ecule exhibits a minor [9.1 (2)%] disorder with methyl-benzyl-idene and benzyl groups inter-changing their positions. The C=N bond length is 1.292 (2) Å. The mol-ecular geometry is essentially planar, with the maximal twist of 8.5 (3)° for the benzyl group. The herringbone packing arrangement does not exhibit any π-stacking inter-acti...

Organosulfates are important components of atmospheric organic aerosols, yet their structures, abundances, sources and formation processes are not adequately understood. This study presents the identification and quantitation of benzyl sulfate in atmospheric aerosols, which is the first confirmed atmospheric organosulfate with aromatic carbon backbone. Benzyl sulfate was identified and quantifi...