Introduction Colon polyp size is a critical biomarker for clinical management of colonic polyps. Larger polyps have a greater malignant potential. During colonoscopy, it is important to correctly measure the size of the polyps because of the direct correlation of size with colon cancer. During polypectomy, size of the colonic polyps encountered are often gauged by visual estimation or the open ...

We have developed a method for the routine primary culture of human colonie epithelial cells. Cultured cells exhibited char acteristic epithelial structures, including a brush border and junctional complexes. Flask-like goblet cells containing mucus were also seen within the epithelial monolayer. [3H]Thymidine labeling indices were used to distinguish between cultured cells from familial polypo...

The purpose of this paper is to assess colonic distension and length and to evaluate a polyp matching algorithm on prone and supine studies in CT colonography (CTC) computer aided diagnosis (CAD). Our CTC CAD software was used to reconstruct the colonic surface, to compute the colon centerline and to detect spatial positions of polyps. Normalized distance along the centerline (NDAC) and colon d...

Over the 8-year period 1971--1978, 743 benign lesions of the larynx, of which 551 were pseudotumors and 192 were benign neoplasms, were surgically treated at Groote Schuur Hospital. In comparison, during the same period 402 malignant tumours of the larynx were also seen. The commonest benign lesions were vocal cord nodules, almost exclusively found in women, and the vocal cord polyp, predominan...

PURPOSE The colonoscopic polypectomy has become a valuable procedure for removing precursors of colorectal cancer, but some complications can be occurred. The most common complication after colonoscopic polypectomy is bleeding, which is reported to range from 1% to 6% and which can be immediate or delayed. Because the management of delayed postpolypectomy bleeding could be difficult, the use of...

BACKGROUND/AIMS Colonoscopic polypectomy is highly efficient in preventing colorectal cancer, but polyps may not always be completely removed. Improved knowledge of the risk factors for incomplete polyp resection after polypectomy may decrease the cancer risk and additional costs. The aim of this study was to investigate the conditions that can cause incomplete polyp resection (IPR) after colon...

Automatic polyp detection is a helpful addition to laborious visual inspection in CT colonography. Traditional detection methods are based on calculating image features at discrete positions on the colon wall. However large-scale surface shapes are not captured. This paper presents a novel approach to aggregate surface shape information for automatic polyp detection. The iso-surface of the colo...

BACKGROUND Large colonic polyps are associated with advanced dysplasia, but prevalence and characteristics of synchronous polyps in patients with large flat colonic polyps are poorly investigated. This study aims to characterize clinicopathological features of large flat colonic polyps and their impact on occurrence and characteristics of synchronous polyps. METHODS A total of 802 patients th...

Collection of multiple resected proximal colon polyps >10 mm in size through a scope channel via aspiration following an endoscopic mucosal resection (EMR) is difficult; thus, polyps are currently all grasped at once using net forceps. However, the simultaneous collection by net forceps makes it difficult to identify the accurate locations of all resected polyps. Therefore, we aimed to investig...

Inflammation is a hallmark of colorectal cancer (CRC). Neutrophils are well-known mediators in tumor biology but their role in solid tumors, including CRC, was redefined by neutrophil extracellular traps (NETs). Given that it was recently demonstrated that platelet-derived polyP primes neutrophils to release NETs, we examined surgical specimens from CRC to investigate the presence of polyP, as ...