Anisotropically refined mixed finite elements are beneficial for the resolution of local features such as boundary layers. Unfortunately, the stability of the resulting scheme is highly sensitive to the aspect ratio of the elements. Previous analysis revealed that the degeneration arises from a relatively small number of spurious (piecewise constant) pressure modes. The present article is conce...

Next Generation Sequencing (NGS) reads obtained by sequencing of the junction of a mobile element and the host flanking region from individuals in a population are typically mapped to a reference genome to determine the location of the mobile element-host junction. We propose a clustering pipeline for grouping such NGS data into clusters corresponding to the locations of integration sites in th...

The toxic element arsenic interacts with the beneficial element silicon at many levels of the plant metabolism. The ability of the tomato plant to take up and translocate As into its fruit has risen concerns that it could facilitate the entry of this element into the human food chain above the admitted level. Here, the fruit of two contrasting tomato cultivars, Aragon and Gladis, were evaluated...

The early fault characteristics of rolling element bearings carried by vibration signals are quite weak because the signals are generally masked by heavy background noise. To extract the weak fault characteristics of bearings from the signals, an improved spectral kurtosis (SK) method is proposed based on maximum correlated kurtosis deconvolution (MCKD). The proposed method combines the ability...

A spectral/hp element discretisation permits both geometric flexibility and beneficial convergence properties to be attained simultaneously. The choice of elemental polynomial order has a profound effect on the efficiency of different implementation strategies with their performance varying substantially for low and high order spectral/hp discretisations. We examine how careful selection of the...

The newly identified apolipoprotein AV (apoAV) gene is a key player in determining plasma triglyceride concentrations. Because hypertriglyceridemia is a major independent risk factor in coronary artery disease, the understanding of the regulation of the expression of this gene is of considerable importance. We presently characterize the structure, the transcription start site, and the promoter ...

A simple and accurate low-blank method has been developed for the analysis of total dissolved copper, cadmium, lead, and iron in a small volume (1.3-1.5 mL per element) of seawater. Pre-concentration and salt-separation of a stable isotope spiked sample are achieved by single batch extraction onto nitrilotriacetate (NTA)-type Superflow(®) chelating resin beads (100-2400 beads depending on the e...

Silicon is the second most abundant element on Earth, and the third most abundant trace element in human body. It is present in water, plant and animal sources. On the skin, it is suggested that silicon is important for optimal collagen synthesis and activation of hydroxylating enzymes, improving skin strength and elasticity. Regarding hair benefits, it was suggested that a higher silicon conte...

Stability of a second-order finite element/finite volume hybrid scheme is investigated on the basis of flows with increasing Weissenberg number. Finite elements are used to discretise the balances of mass and momentum. For the stress equation a finite volume method is used, based on the recent development with fluctuation distribution schemes for pure convection problems. Examples considered in...

Tramadol® (analgesic of the landing 2) is a centrally acting analgesic with a dual mode of action. Its analgesic efficacy is attributed to its partial affinity for the (μ) mu-opiate receptor and its inhibition of noradrenaline and serotonin reuptake. Acting in a synergistic manner and being more efficacious, Tramadol® is used worldwide for the treatment of moderate to severe acute or chronic pa...