Rodents post-weaning isolation could be considered a significant early-life model of chronic stress. The aim our study was to investigate the effects female rats on different behavioral tests and neurochemical parameters. On postnatal day 21, pups were housed either isolated or socially in groups (4/cage) for 6 weeks. After 6th week adult behaviorally examined using open field test, three chamb...

Abstract Background Recent research has developed a better appreciation for non‐cognitive factors, such as neuropsychiatric symptoms (NPS), early indicators dementia. This led to the development of criteria mild behavioral impairment (MBI), or late‐life onset NPS. MBI been associated with unique cognitive phenotype, but on longitudinal changes is limited. The goal this study examine if influenc...