DNA microarray technology can measure the activities of tens of thousands of genes simultaneously, which provides an efficient way to diagnose cancer at the molecular level. Although this strategy has attracted significant research attention, most studies neglect an important problem, namely, that most DNA microarray datasets are skewed, which causes traditional learning algorithms to produce i...

This study was performed to investigate whether elderly patients with imbalance can be distinguished from healthy elderly subjects by comparing their whole body center of mass (COM) motion in the medio-lateral (M-L) direction during obstacle crossing. Nine healthy elderly adults and six elderly patients having complaints of 'dizziness' or 'unsteadiness' during walking (three with bilateral/unil...

PURPOSE When observers focus their stereoscopic visual system for a long time (e.g., watching a 3D movie) they may experience visual discomfort or asthenopia. We tested two types of models for predicting visual fatigue in a task in which subjects were instructed to discriminate between 3D characters. One model was based on viewing distance (focal distance, vergence distance) and another in visu...

Pregnancy-induced nausea and vomiting (PINV) is a common problem at the early stages of pregnancy. Approximately, 50%–80% of pregnant women who are in their first trimester are affected, resulting in loss of work time and negative effects on social and family relationships (1). Hyperemesis gravidarum (HG) affects approximately 2.5% of pregnant woman and is characterized by persistent vomiting, ...

Class imbalance data usually suffers from data intrinsic properties beyond that of imbalance alone. The problem is intensified with larger levels of imbalance most commonly found in observational studies. Extreme cases of class imbalance are commonly found in many domains including fraud detection, mammography of cancer and post term births. These rare events are usually the most costly or have...

Kidneys are central metabolic organs in our body. They regulate our water and electrolyte balance amongst other things, and are responsible for the removal of potentially toxic substances and medications. Shockingly, many of today’s widespread diseases can lead to damaged kidneys and an impairment of their function. Chronic renal failure is a systemic disease with massive effects on the whole o...

The present paper provides a review of 45 studies on the Effort-Reward Imbalance (ERI) Model published from 1986 to 2003 (inclusive). In 1986, the ERI Model was introduced by Siegrist et al. (Biological and Psychological Factors in Cardiovascular Disease, Springer, Berlin, 1986, pp. 104-126; Social Science & Medicine 22 (1986) 247). The central tenet of the ERI Model is that an imbalance betwee...

Hyponatremia is the most common electrolyte imbalance encountered in clinical practice. Beside the difficulty of the etiological diagnosis, the general lack of awareness regarding the negative impact of hyponatremia on the quality of life and the lack of targeted treatments until recent years may be responsible for the poor management of the disorder. Therefore we consider of utmost importance ...