BACKGROUND The development of new drugs or alternative therapies effective against methicillin-resistant Staphylococcus aureus (MRSA) is of great importance, and various natural anti-MRSA products are good candidates for combination therapies. We evaluated the antibacterial activities of a Phellinus baumii ethyl acetate extract (PBEAE) and its synergistic effects with β-lactams against MRSA. ...

In addition to Ag recognition, some Abs are capable of killing target organisms in the absence of phagocytes and complement. In this study, we report that an anti-Pseudomonas aeruginosa O6ad LPS IgG(1), tobacco-expressed human S20 IgG(1) (te-hS20), as well as its recombinant Fab and single-chain variable fragment (scFv) fragments have cellular- and complement-independent bactericidal activity. ...

Increasing resistances of germs to established antiseptics demand a continuous development of new antimicrobial agents. Therefore, atmospheric pressure plasma was used to produce antimicrobial NaCl-solutions. Its shortand long-term germicidal effects have been investigated by inactivation of Escherichia coli in batches. Liquid changes by plasma exposure that correlate with bacteria inactivation...

Data derived from testing the bactericidal activity of combinations of penicillin with gentamicin or streptomycin and of clindamycin with gentamicin on nine isolates of Streptococcus mutans were analyzed by preparing isobolograms to determine the presence of additive, synergistic, or antagonistic effects. Synergy with penicillin-aminoglycoside combinations was found in two strains; additive eff...

In the preceding paper (1), it was reported that rat leucocyfic extracts prepared by ultrasonic disintegration of polymorphonuclear neutrophils (leucocytes) were bactericidal against both Gram-negative and Gram-positive organisms. The bactericidal activity of these extracts was confined primarily to the mitochondria. The purpose of this report is to characterize this bactericidal substance or s...

Of five parenteral cephalosporins tested against 43 lactobacilli, cephaloridine, cefazolin, and cefamandole were the most active inhibitory and bactericidal agents. Timed-kill analysis revealed a slow bactericidal effect, with significant declines in mean minimal bactericidal concentration values at 48 h versus 24 h.

as frequent in those with bactericidal activity (54%) as in those without (56%). The coexistence of bactericidal activity and bacteremia was reproduced and studied in experimentally infected weanling rats. Serum from such rats kills in vitro 95% of conventionally broth-grown bacteria within 10 min, but does not kill organisms obtained from the infected animals. Thus bactericidal activity as con...

Recently, the effects of antimicrobial activity of silver nanoparticles was considered by researcher because of Bacterial resistance to antimicrobial agents in chemical.The aim of this study was to evaluate the antimicrobial activity of the gold nanoparticles on Escherichia coli. Gold nanoparticles are chemically synthesized. Standard strain of E. coli was cultured in a nutrient broth. Minimum ...

Vibrio cholerae is a human pathogen that causes mild to severe diarrheal illnesses and has major public health significance. The aim of this study was to investigate the effects of antimicrobial activity of the gold nanoparticles on Vibrio cholera. Gold and Silver nanoparticles are chemically synthesized. Standard strain of Vibrio cholerawas cultured in a nutrient broth. Minimum inhibitory conc...

Vibrio cholerae is a human pathogen that causes mild to severe diarrheal illnesses and has major public health significance. The aim of this study was to investigate the effects of antimicrobial activity of the gold nanoparticles on Vibrio cholera. Gold and Silver nanoparticles are chemically synthesized. Standard strain of Vibrio cholerawas cultured in a nutrient broth. Minimum inhibitory conc...