Paediatric bacterial meningitis is a serious infection that can result in permanent neurological sequelae or death. Broad-spectrum intravenous antibiotics, started as soon as the condition is suspected, are the mainstay of treatment. Acute resuscitation may also be necessary for patients who are in septic shock. Corticosteroids, careful fluid management and advances in intensive care therapy ha...

The worldwide spread of multidrug-resistant organisms has required the development of new antimicrobials. Linezolid, the first oxazolidinone, has a broad spectrum of activity against Gram-positive bacteria, including resistant strains. Although approved by the Food and Drug Administration in 2002, the clinical experience with linezolid in the paediatric population is still limited, also given t...

Prolonged drought results in serious ecological consequences forest ecosystems, particularly for soil microbial communities. However, much is unknown about communities their response to long-term consecutive droughts warm-temperate forests. Here, we conducted a 7-year manipulated throughfall reduction experiment (TFR) examine the responses of bacterial and fungal terms richness networks. Our sh...

Bacterial biofilm is an emerging clinical problem recognized in the treatment of infectious diseases within the last two decades. The appearance of microbial biofilm in clinical settings is steadily increasing due to several reasons including the increased use of quality of life-improving artificial devices. In contrast to infections caused by planktonic bacteria that respond relatively well to...

Removal of the predisposing condition, appropriate nutritional support to reintegrate both caloric and vitamin requirements and suppression of the contaminating bacterial flora represent the main of goals of the treatment of small intestine bacterial overgrowth. Generally, the polymicrobic nature of contaminating flora requires the administration of wide-spectrum antibiotics, but as yet we don'...

Bacteria present in the root canal (RC) space following an RC treatment (RCT) can lead to persistent infections, resulting in treatment failure and the need for reintervention or extraction. Currently, there are no standardized methods in use to clinically detect bacterial presence within RC spaces. The use of paper point sampling and fluorescence staining was shown to be a rapid method, able t...