AIMS To determine the quantitative relation between the major risk factors for microbial keratitis of previous ocular surface disease and contact lens wear and central and peripheral infiltration, often associated with ulceration, in order to establish a rational chemotherapeutic management algorithm. METHODS Data from 55 patients were collected over a 10 month period. All cases of presumed m...

Bacterial infections ofthe anterior segment ofthe eye are not a common feature of AIDS but once established these infections may be particularly severe and more likely to cause ulcer and perforation.' Pseudonwmas aeruginosa has been cultured in keratitis, corneal ulcers, and scleritis in HIV infected patients2; nevertheless, nobody has previously reported Pseudomonas conjunctival ulcers in HIV ...

We describe the clinical course and successful treatment of two cases of methicillin-resistant Staphylococcus aureus (MRSA) keratitis. In case 1, MRSA keratitis occurred 5 days after cataract extraction, associated with endophthalmitis; in case 2, diagnosis was made 19 months after penetrating keratoplasty. Treatment in both cases consisted of topical fortified vancomycin and fortified bacitrac...

The red eye is one of the most common presentations to health care centres. red-eye can be divided into painless and painful. includes bacterial, viral, allergic conjunctivitis, dry eyes, episcleritis subconjunctival haemorrhage. Meanwhile, painful more challenging, as some involve ophthalmic emergencies which are acute angle-closure attack, anterior uveitis, scleritis, orbital cellulitis, seve...

Pseudomonas aeruginosa infections are difficult to treat due to the presence of a multitude of virulence factors and antibiotic resistance. Here, we report the draft genome sequence of P. aeruginosa BK1, an invasive and multidrug-resistant strain, isolated from a bacterial keratitis patient in southern India.

the objectives of this study were to define the clinical risk factors, microbiological spectrum, and visual outcome of bacterial keratitis at shahid sadoughi hospital (yazd, iran). a crosssectional prospective study, identified 80 cases of microbial keratitis from march 1999 to march 2001. inclusion criteria were presence of corneal stromal infiltrate in slit lamp examination, and microbiologic...

PURPOSE To explore the role of lithium chloride (LiCl) in Pseudomonas aeruginosa (PA) keratitis. METHODS B6 mice were subconjunctivally injected with LiCl in contrast to appropriate control sodium chloride (NaCl), and then routinely infected with PA. Clinical score, slit-lamp photography, hematoxylin and eosin (H&E) staining, and bacterial plate counts were used to determine the role of LiCl ...

PURPOSE To describe a case of fungal keratitis involving an atypical organism with confirmatory in vivo confocal microscopy and to review the literature on Rhodotorula keratitis. METHODS Case report and review of the medical literature. RESULTS A 22-year-old college student was struck in the left eye with a tree branch and subsequently developed pain, redness and photophobia. Upon presentat...

BACKGROUND Fungal keratitis is a suppurative, ulcerative, and sight-threatening infection of the cornea that sometimes leads to loss of the eye. The objectives of this study were to improve facilities for laboratory diagnosis, to determine the predominant causative microorganisms, and to identify the predisposing factors of mycotic keratitis patients. METHODS A prospective study of corneal ul...

AIMS/BACKGROUND In adult tissues the expression of tenascin-cytotactin (TN-C), an extracellular matrix glycoprotein, is limited to tumours and regions of continuous renewal. It is also transiently expressed in cutaneous and corneal wound healing. There are limited data regarding its expression in inflammation and scarring of the adult human cornea. In this study, TN-C expression patterns in nor...