INTRODUCTION Antibiotics are used to treat bacterial infections by killing the bacteria or inhibiting their growth, but resistance to antibiotics can develop readily. The discovery that bacterial quorum-sensing regulates bacterial virulence as well as the formation of biofilms opens up new ways to control certain bacterial infections. Furanone compounds capable of inhibiting bacterial quorum-se...

Influenza virus neuraminidase (NA) cleaves terminal sialic acid residues on oligosaccharide chains that are receptors for virus binding, thus playing an important role in the release of virions from infected cells to promote the spread of cell-to-cell infection. In addition, NA plays a role at the initial stage of viral infection in the respiratory tract by degrading hemagglutination inhibitors...

BACKGROUND Mixed bacterial infection is an important contributor to morbidity and mortality during influenza pandemics. We evaluated procalcitonin (PCT) and C-reactive protein (CRP) in differentiating pneumonia caused by mixed bacterial and 2009 H1N1 influenza infection from 2009 H1N1 influenza infection alone. METHODS Data were collected retrospectively over a 7-month period during the 2009 ...

background and objectives: urinary tract infection (uti) is one of the most common infections and a major cause of patient morbidity world wide. the gold standard for detection of bacterial pathogens in uti is culture of urine specimens. in order to facilitate identification of bacterial pathogens in clinical urine specimens we designed a molecular method to detect bacterial pathogen in uti. ma...

Correspondence to: Professor A K Burroughs, Liver Transplantation and Hepatobiliary, Medicine Unit, Royal Free Hospital, Pond St, London NW3 2QG, UK; Andrew.Burroughs@ royalfree.nhs.uk _________________________ SUMMARY Bacterial infections in cirrhotic patients are common. There is a predisposition to intestinal bacterial overgrowth, intestinal dysmotility, and increased intestinal permeability...

Cavernous sinus thrombosis is a life-threatening condition that arises as complication of facial infection, sinusitis, orbital cellulitis, pharyngitis, or otitis fungal bacterial origin after traumatic injury surgery. Rhinocerebral mucormycosis an aggressive infection that, depending on its level extension, affects nasal passages, paranasal sinuses and the region.

Duplex SERS-based lateral flow testing for C. diff bacterial infection using new biomarker, SlpA, and ToxB within 20 minutes.

A central problem in infection biology is understanding why two individuals exposed to identical infections have different outcomes. We have developed an experimental model where genetically identical, co-housed Drosophila given identical systemic infections experience different outcomes, with some individuals succumbing to acute infection while others control the pathogen as an asymptomatic pe...

BACKGROUND Recognizing infection is crucial in immunocompromised patients with organ dysfunction. Our objective was to assess the diagnostic accuracy of procalcitonin (PCT) in critically ill immunocompromised patients. METHODS This prospective, observational study included patients with suspected sepsis. Patients were classified into one of three diagnostic groups: no infection, bacterial sep...

in order to investigate the prevalence of mannheimia haemolytica infection in cattle, nasal andnasopharyngeal swabs and blood samples were obtained from 250 cattle after slaughter at ahvaz(southwestern iran) abattoir. nasal and nasopharyngeal swabs were cultured on blood agar and incubated at37°c for 24-48 h. the suspected bacterial cultures were processed for isolation of m. haemolytica follow...