نتایج جستجو برای: axillary metastasis
تعداد نتایج: 141073 فیلتر نتایج به سال:
OBJECTIVE This is a retrospective study to compare the clinicopathological features between young and elderly women with breast cancer. METHODS Totally 181 young and 186 elderly breast cancer patients were analyzed and compared in respects of the histological subtype, tumor number and size, tumor location, histological grading, UICC-pTNM pathological staging, and lymph node metastasis status....
Sentinel lymph node (SLN) status is highly predictive of overall axillary lymph node involvement in breast cancer. Historically, SLN-positive patients have undergone axillary lymph node dissection in a second surgery. Intraoperative SLN analysis could reduce the cost and complications of a second surgery; however, existing histopathological methods lack standardization and exhibit poor sensitiv...
Parathyroid Hormone Secreting Metaplastic Breast Carcinoma: A Case Report of Paraneoplastic Syndrome
Paraneoplastic syndrome (PNS) is a distant neurological manifestation of an underlying tumour. Humoral hypercalcaemia of malignancy is a form of paraneoplastic syndrome where there is an increased in calcium levels. In this article we report a 48 year old lady, with no known medical illness and presented with symptomatic hypercalcaemia. She presented to our institution complaining of a fungatin...
Introduction: Post-irradiation mammary stromal sarcoma (MSS) is a rare condition, and it worth learning new knowledge from each case. Case Presentation: We present the case report of 59-year-old female with medical history breast cancer, who presented an axillary mass on same side. The patient was further evaluated finally diagnosed MSS chondroid differentiation. Thereafter, she underwent neoad...
Axillary lymph node dissection represents the standard surgical treatment for breast cancer patients with clinically or histologically involved axillary lymph nodes. However, it is associated with significant morbidity, including postoperative arm lymphedema and neuropathy of the involved extremity, and seroma formation in the axilla (Noguchi et al., 1997). Particularly, arm lymphedema develops...
DNA double-strand break (DSB) is one of the most deleterious lesions induced by DNA damaging agents. DSB repair pathway is implicated in maintaining genomic integrity via suppression of genetic instability and neoplastic transformation. DNA-dependent protein kinase (DNA-PK) has a pivotal role in DNA DSB repair. The Nijmegen breakage syndrome protein (NBS1), essential for DSB repair, re-localize...
Axillary lymph node dissection (ALND) or sentinel lymph node biopsy (SLNB) alone may lead to postoperative complications. Among patients with positive ALN in the preoperative examination, approximately 40% patients do not have SLN metastasis. Herein, we aimed to develop a model to predict the probability of ALN metastasis as a preoperative tool to support clinical decision-making. We retrospect...
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