BACKGROUND To compare refractive index variation between Hoffer-Q, Haigis and SRK/T formulas used for preoperative biometry calculation in patients with axial length >25 mm, undergoing cataract surgery. MATERIALS AND METHODS This is a randomized clinical trial study was performed on 54 eyes of 54 patients with ages of 40-70 years old and axial length >25 mm classified into three groups that t...

PURPOSE To analyze the relationship between transforming growth factor-beta 2 (TGF- β 2) levels in the anterior chamber aqueous humor and axial length of patients with myopia. METHODS TGF- β 2 was measured with the Luminex xMAP Technology by using commercially available Milliplex xMAP Kits. Sixty-five aqueous humor samples were collected during cataract or clear lens extraction surgery and TG...

purpose: to determine the effect of induced myopia and hyperopia using soft contact lenses on optic disc parameters measured by fourier domain optical coherence tomography (fd-oct) in emmetropic persons. methods: in a quasi-experimental self controlled study, 57 normal emmetropic participants 18-42 years of age were studied. each subject underwent a complete ophthalmic examinations including me...

Deprivation of form vision restricted to a region of the retina produces myopia and axial elongation only in that region. We asked whether this control of eye growth by the presence or absence of visual stimuli might take place entirely within the eye. Chicks with neonatal optic nerve section, wearing an occluder that deprived one half of the retina of form vision, had vitreous chamber elongati...

The relationship between axial length and equatorial diameter and eye volume has been studied in 4 groups of eyes: intact emmetropic eyes, emmetropic eyes with retinal detachment, eyes with moderate myopia and retinal detachment, and eyes with high myopia and retinal detachment. It was found that eyes with detached retinas, regardless of whether they are myopic or emmetropic, are of significant...

Acquired esotropia with high myopia may be associated with superotemporal eyeball prolapse from the muscle cone and the subsequent shift of extraocular muscles limits the success of the traditional recession-resection surgery. In this study, we report two patients diagnosed with myopic strabismus fixus with esodeviation >90 prism diopter. Marked axial elongation of globes was present in both th...

Twenty hatchling chickens were injected intravitreally every 4 days from day 2 to day 16 with dimethyl sulphoxide (DS) in one eye and DS or formoguanamine dissolved in DS (FG.DS) with or without occlusion in the other (FG.DS.MD, DS.MD, FG.DS). At day 16, the FG.DS.MD eyes failed to show the high refractive myopia and showed less axial elongation than that developed by the DS.MD eyes. Electroret...

OBJECTIVE To determine the correlation between multifocal electroretinogram (mfERG) parameters and the severity of myopia in adults and children. DESIGN Observational study. METHODS Multifocal electroretinograms were recorded using the VERIS system from randomly selected eyes of 104 children and 31 adults with various degrees of myopia. Dawson, Trick, and Litzkow fiber electrodes were used ...

Lumican (LUM) is a candidate gene for myopia in the MYP3 locus. In this study, a mutant lumican (L199P) transgenic mouse model was established to investigate the axial length changes and ultrastructural features of the sclera. The mouse model was established by pronuclear microinjection. Transgenic mice and wild-type B6 mice were killed at eight weeks of age. Gene expression levels of LUM and c...

When lids are surgically fused in rhesus monkeys before eye growth is completed, a high degree of myopia develops, which is caused by an elongation of the eye globe. The present study shows that in monkeys raised in the dark after monocular lid fusion, refraction and axial length were normal in both the closed and the open eye. Myopia, however, readily developed and the eye elongated when a mon...