Pada dasarnya tidak semua aparatur sipil negeri (ASN) memiliki citra positif dalam persepsi masyarakat. Hal tersebut terlihat misalnya dari kurangnya disiplin ASN. Untuk menyikapi hal Pemerintah Republik Indonesia melakukan Latihan Dasar (Latsar) bagi seluruh calon pegawai (CPNS) yang dilaksanakan oleh Badan Pengembangan Sumber Daya Manusia. Tujuan penelitian ini mendeskripsikan kegiatan selama...

N-linked glycosylation can profoundly affect protein expression and function. N-linked glycosylation usually occurs at the sequon Asn-Xaa-Ser/Thr, where Xaa is any amino acid residue except Pro. However, many Asn-Xaa-Ser/Thr sequons are glycosylated inefficiently or not at all for reasons that are poorly understood. We have used a site-directed mutagenesis approach to examine how the Xaa and hy...

In most prokaryotes Asn-tRNA(Asn) and Gln-tRNA(Gln) are formed by amidation of aspartate and glutamate mischarged onto tRNA(Asn) and tRNA(Gln), respectively. Coexistence in the organism of mischarged Asp-tRNA(Asn) and Glu-tRNA(Gln) and the homologous Asn-tRNA(Asn) and Gln-tRNA(Gln) does not, however, lead to erroneous incorporation of Asp and Glu into proteins, since EF-Tu discriminates the mis...

Recent evidence suggests that amyloidogenic oligomers may be the toxic species in cell cultures. Thus, it is crucial to understand their structure and oligomerization mechanism in atomistic detail. By employing tens of fast central processing units and an advanced phase-space sampling algorithm, parallel-tempering molecular dynamics, we have explored the energy landscape of amyloidogenic peptid...

Ad-hoc Social Network (ASN) is a social network based on ad-hoc network. The paper describes the work done for implementation of ASN, to determine user experience while using ASN on mobile network, architecture of ASN and different profile matching algorithms. The paper also proposes some of research issues and challenges to be solved for ASN. Index Terms – Ad-hoc Social Network, Routing, Profi...

LSI78Y mouse lymphoblastic leukemia cells normally require asparagine (ASN) for growth, but phenotypically stable ASN-independent cells are detectable at low fre quency by direct cloning, in ASN-free soft-agar medium, of cells from cultures that have been grown nonselectively in medium containing ASN. The rate of mutation in vitro to ASN independence was determined by the Luria-Delbruck fluctua...

Ray, Ramesh M., Mary Jane Viar, Tarun B. Patel, and Leonard R. Johnson. Interaction of asparagine and EGF in the regulation of ornithine decarboxylase in IEC-6 cells. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G773–G780, 1999.—Our laboratory has shown that asparagine (ASN) stimulates both ornithine decarboxylase (ODC) activity and gene expression in an intestinal epithelial cell lin...